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Name Reactions pp 428-428 | Cite as

Weinreb amide

  • Jie Jack Li

Abstract

N-Methoxy-N-methyl-amide. Due to the chelation effect, nucleophilic addition of an organometallic reagent adds only once to give ketone, whereas normal amides would have led to double addition to afford tertiary alcohol.

Keywords

Inorganic Chemistry Organic Chemistry Nucleophilic Addition Tertiary Alcohol Chelation Effect 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • Jie Jack Li
    • 1
  1. 1.Chemistry DepartmentPfizer Global Research and DevelopmentAnn ArborUSA

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