Advertisement

Name Reactions pp 340-340 | Cite as

Robinson annulation

  • Jie Jack Li

Abstract

Michael addition of cyclohexanones to methyl vinyl ketone followed by intramolecular aldol condensation to afford six-membered α,β-unsaturated ketones.

Keywords

Inorganic Chemistry Organic Chemistry Michael Addition Formation Addition Aldol Condensation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Rapson, W. S.; Robinson, R. J. Chem. Soc. 1935, 1285.Google Scholar
  2. 2.
    Gawley, R. E. Synthesis 1996, 777. (Review).Google Scholar
  3. 3.
    Bui, T.; Barbas, C. F., III Tetrahedron Lett. 2000, 41, 6951.CrossRefGoogle Scholar
  4. 4.
    Jansen, B. J. M.; Hendrix, C. C. J.; Masalov, N.; Stork, G. A.; Meulemans, T. M.; Macaev, F. Z.; De Groot, A. Tetrahedron 2000, 56, 2075.CrossRefGoogle Scholar
  5. 5.
    Guarna, A.; Lombardi, E.; Machetti, F.; Occhiato, E. G.; Scarpi, D. J. Org. Chem. 2000, 65, 8093.CrossRefGoogle Scholar
  6. 6.
    Tai, C.-L.; Ly, T. W.; Wu, J.-D.; Shia, K.-S,; Liu, H.-J. Synlett 2001, 214.Google Scholar
  7. 7.
    Jung, M. E.; Piizzi, G. Org. Leu. 2003, 5, 137.CrossRefGoogle Scholar
  8. 8.
    Liu, H.-J.; Ly, T. W.; tai, C.-L.; Wu, J.-D. et al. Tetrahedron 2003, 59, 1209.CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • Jie Jack Li
    • 1
  1. 1.Chemistry DepartmentPfizer Global Research and DevelopmentAnn ArborUSA

Personalised recommendations