The Nuclear Medicine Point of View in Orthopaedic Infections: Imaging with Tc-99m-Ciprofloxacin, Infecton

  • K. E. Britton
Conference paper


Tc-99m radiolabelled ciprofloxacin, which we call Infecton, was first described by the radiopharmacist K. Solanki, who noted that the effectiveness of ciprofloxacin diminishes when taken with iron. He postulated that this was because of chelation of the iron with the antibiotic. He, therefore, prophesied that he could chelate technetium-99m to the antibiotic and this would lead to technetium-99m-ciprofloxacin.


International Atomic Energy Agency Septic Arthritis Hexamethyl Propyleneamine Bone Marrow Uptake Orthopaedic Infection 
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© Springer-Verlag Berlin Heidelberg 2003

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  • K. E. Britton

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