Malignant Tumors of the Central Nervous System

  • Robert G. Parker
  • Nora A. Janjan
  • Michael T. Selch
Part of the Medical Radiology book series (MEDRAD)


In 2001, in the United States, there were approximately 17,200 new diagnoses of cancers of “the brain and other nervous systems”, with 13,100 consequent cancer-related deaths [1]. Men were affected more often that women in the ratio of 1.3:1. In the adult, metastases were several times more frequent than primary tumors [2, 3]. Primary tumors of the central nervous system (CNS) make up about 1.5% of all cancers and 2.5% of all cancer-related deaths [4]. Spinal cord tumors, both primary and metastatic, are about 10% as frequent as cerebral tumors [5]. Although the incidence of primary CNS tumors increases with increasing age, these tumors are proportionately more frequent in childhood [6], when primary CNS tumors are the most frequent solid cancers, with an incidence of 2–3 per 100,000 and are the second most frequent cause of cancer-related deaths [6, 7]. The most frequent primary tumors in children are medulloblastoma and low-grade astrocytoma [6].


Radiat Oncol Biol Phys Primary Central Nervous System Lymphoma Radiation Therapy Oncology Group Central Nervous System Tumor Spinal Cord Tumor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • Robert G. Parker
    • 1
  • Nora A. Janjan
    • 2
  • Michael T. Selch
    • 1
  1. 1.Department of Radiation Oncology, UCLA School of MedicineUniversity of California, Los AngelesLos AngelesUSA
  2. 2.Department of Radiation OncologyM.D. Anderson Cancer CenterHoustonUSA

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