Abstract
Experimental and clinical observations have demonstrated therapeutic effects of ionizing radiation on mature and proliferating vessels. On the basis of these results, it was thought that radiation therapy might well be helpful in neovascular late stages of age-related macular degeneration (AMD). The ocular tissues exhibit differing radiation effects, so that the high susceptibility of proliferating endothelial cells to radiation seemed to provide a scientific rationale for a new therapeutic approach to choroidal neovascularization (CNV).
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Schütt, F., Bellmann, C., Bindewald, A., Engenhart-Cabillic, R., Debus, J., Holz, F.G. (2004). Radiation Therapy. In: Age-related macular degeneration. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-05199-3_13
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DOI: https://doi.org/10.1007/978-3-662-05199-3_13
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