Ion Channels

  • Poul Bennekou
  • Palle Christophersen


Erythrocyte ion channels have been described from several animal species and have been more or less extensively characterized. However, the most comprehensive picture has been established for mammalian erythrocytes, especially human, which will be the focus of this chapter. Among the pathways for passive, conductive transport of inorganic ions, two different cation channels have been extensively characterized at present, an intermediate conductance Ca2+-activated K+ channel, also known as the Gárdos channel, and a voltage-dependent non-selective cation channel. It should be remembered, however, that transport mediated by these channels was observed decades before ion channels were established facts of life.


Single Channel Conductance Positive Membrane Potential Open State Probability Human Erythrocyte Ghost Gardos Channel 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • Poul Bennekou
    • 1
  • Palle Christophersen
    • 2
  1. 1.LCMF, The August Krogh InstituteUniversity of CopenhagenCopenhagen ØDenmark
  2. 2.NeuroSearch A/S, BallerupBallerupDenmark

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