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Biochips pp 11-34 | Cite as

Medical Therapy: The Next Frontier of Biochip and Biomedical Nanotechnology

  • M. Ferrari
  • D. Friend
  • D. Hansford
  • S. S. Kulkarni
  • F. Martin
Chapter
  • 201 Downloads
Part of the Biological and Medical Physics Series book series (BIOMEDICAL)

Abstract

In the recent past rapid strides have been made to exploit the applications of nanotechnology in biomedical applications. While the focus of such research has primarily been on diagnostic tools, the therapeutic applications have not been so widely researched. This chapter seeks to review the state of the art of nanotechnology in therapeutic applications.

The manipulation of conventional lithographic techniques to produce monodisperse nanoporous, biocompatible, silicon membranes has been described. The potential use of these microfabricated nanoporous membranes in site-specific drug delivery applications has been investigated and their use in the fabrication of immunoisolating biocapsules has been elucidated. Specifically, an insulin-delivering microfabricated biocapsule has been described. Using the same nanotechnlogy principles, an innovative, nanotechnology-based systemic treatment method for metastatic deposits, employing a microfabricated Natural Killer (NK) mimicking cell has been propounded.

Keywords

Natural Killer Cell Sacrificial Layer Silicon Membrane Cell Encapsulation Conventional Lithography 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • M. Ferrari
  • D. Friend
  • D. Hansford
  • S. S. Kulkarni
  • F. Martin

There are no affiliations available

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