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Elucidating Molecular Mechanisms of Alzheimer’s Disease in Microglial Cultures

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Neuroinflammation — From Bench to Bedside

Part of the book series: Ernst Schering Research Foundation Workshop ((SCHERING FOUND,volume 39))

Abstract

Particularly in the context of innate inflammatory mechanisms, micro-glia appear to play important roles in a wide range of neurodegenerative diseases, including multiple sclerosis, Parkinson’s disease, and human immunodeficiency virus (HIV)-associated dementia (reviewed in Banati et al. 1993; Dickson et al. 1993; McGeer et al. 1993). It should not be surprising, then, that microglial activation has been found to be a crucial event mediating inflammatory responses in Alzheimer’s disease (AD) (reviewed in Neuroinflammation Working Group 2000).

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  1. J. Rogers
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  2. L.-F. Lue
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  3. D. G. Walker
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  4. S. D. Yan
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  5. D. Stern
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  6. R. Strohmeyer
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  7. C. J. Kovelowski
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Editor information

Editors and Affiliations

  1. Max Delbrück Center for Molecular Medicine, Department of Neurosciences, Robert Roessle Str. 10, 13125, Berlin, Germany

    H. Kettenmann

  2. Preclinical Drug Research, Schering AG, Müllerstr. 178, 13342, Berlin, Germany

    G. A. Burton  & U. J. Moenning  & 

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Rogers, J. et al. (2002). Elucidating Molecular Mechanisms of Alzheimer’s Disease in Microglial Cultures. In: Kettenmann, H., Burton, G.A., Moenning, U.J. (eds) Neuroinflammation — From Bench to Bedside. Ernst Schering Research Foundation Workshop, vol 39. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-05073-6_3

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  • DOI: https://doi.org/10.1007/978-3-662-05073-6_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-05075-0

  • Online ISBN: 978-3-662-05073-6

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