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Introduction

  • Susanne Hummel
Chapter

Abstract

The major work that occurred in scientific research in the field of ancient and degraded DNA in the 1980s laid the groundwork for today’s investigations. In the very beginning of that decade, a group of Chinese researchers from the Hunan Medical School proved that DNA is preserved in the tissues of ancient bodies (1980) (Fig. 1.1). Just 1 year later, Anderson and his colleagues published the fully sequenced human mitochondrial genome (1981). The next year, microsatellite DNA, socalled short tandem repeats (STR), was discovered by Hamada and colleagues (1982); it was later recognized that these enable a fingerprinting similar to DNA typing. A crucial event for ancient DNA research was the invention of the polymerase chain reaction, which enables the amplification of DNA into highly sensitive and simple assays better than any other molecular technique (Saiki et al. 1985; Mullis and Faloona 1987). Around the same time, western researchers from very different fields also published their first results on the extraction of DNA from preserved tissues. Higuchi et al. (1984) succeeded in the extraction of DNA from quagga, an extinct member of the horse family (Fig. 1.2), and Johnson et al. (1985) investigated the DNA they had extracted from mammoth remains.

Keywords

Short Tandem Repeat Skeletal Remains Yersinia Pestis Short Tandem Repeat Marker Mass Disaster 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Allmann M, Höfelein C, Koppel E, Lüthy J, Meyer R, Niederhauser C, Wegmüller B, Candrian U(1995) Polymerase chain reaction (PCR) for detection of pathogenic microorganisms in bacteriological monitoring of dairy products. Res Microbiol 146:85–97CrossRefGoogle Scholar
  2. Alonso A, Andelinovic S, Martin P, Sutlovic D, Erceg I, Huffine E, de Simon LF, Albarran C, Definis-Gojanovic M, Fernandez-Rodriguez A, Garcia P, Drmic I, Rezic B, Kuret S, Sancho M, Primorac D (2001) DNA typing from skeletal remains: evaluation of multiplex and megaplex STR systems on DNA isolated from bone and teeth samples. Croat Med J 42:260–266Google Scholar
  3. Altshuler D, Pollara VJ, Cowles CR, Van Etten WJ, Baldwin J, Linton L, Lander ES (2000) An SNP map of the human genome generated by reduced representation shotgun sequencing. Nature 407:513–516CrossRefGoogle Scholar
  4. Anderson S, Bankier A, Barrell B, De Bruijn M, Coulson A, Drouin J, Eperon I, Nierlich D, Roe B, Sanger F, Schreier P, Smith A, Staden R, Young I (1981) Sequence and organization of the human mitochondrial genome. Nature 290:457–465CrossRefGoogle Scholar
  5. Anslinger K, Weichhold G, Keil W, Bayer B, Eisenmenger W (2001) Identification of the skeletal remains of Martin Bormann by mtDNA analysis. Int J Legal Med 114:194–196CrossRefGoogle Scholar
  6. Asenbauer B, McEntagart M, King MD, Gallagher P, Burke M, Farrell MA (1998) Chronic active destructive herpes simplex encephalitis with recovery of viral DNA 12 years after disease onset. Neuropedeatrics 29:120–123CrossRefGoogle Scholar
  7. Back JP, Langford SA, Kroll RG (1993) Growth of Listeria monocytognes in camembert and other soft cheese at refrigeration temperatures. J Dairy Res 60:421–429CrossRefGoogle Scholar
  8. Baron H, Hummel S, Herrmann B (1996) Mycobacterium tuberculosis complex DNA in ancient human bones. J Archaeol Sci 23:667–671CrossRefGoogle Scholar
  9. Barriel V, Thuet E, Tassy P (1999) Molecular phylogeny of Elephantidae. Extreme divergence of the extant forest African elephant. C R Académie des Sciences 322:447–454CrossRefGoogle Scholar
  10. Boerwinkle E, Xiong W, Fourest E, Chan L (1989) Rapid typing of tandemly repeated hypervariable loci by the polymerase chain reaction: application to the apolipoprotein B 3’ hypervariable. Proc Natl Acad Sci USA 86:212–216CrossRefGoogle Scholar
  11. Bollongino R (2000) Bestimmung humanökologisch relevanter Tierarten aus historischen, musealen und forensischen Materialien durch Sequenzierung mitochondrialer Genorte. Diplomarbeit, Georg August-Universität, GöttingenGoogle Scholar
  12. Bramanti B, Hummel S, Schultes T, Herrmann B (2000a) STR allelic frequencies in a German skeleton collection. Anthrop Anz 58:45–49Google Scholar
  13. Brarranti B, Hummel S, Schultes T, Herrmann B (2000b) Genetic characterization of an historical human society by means of aDNA analysis of autosomal STRs. In: Susanne C, Bodzar EB (eds) Human populations genetics in Europe. Biennial Books of EAA 1:147–163Google Scholar
  14. Brown CM, Cann JW, Simons G, Frankhauser RL, Thomas W, Parashar OD, Lewis MJ (2001) Outbreak of Norwalk virus in a Caribbean island resort: application of molecular diagnostics to ascertain the vehicle of infection. Epidemiol Infect 126:425–432CrossRefGoogle Scholar
  15. Brown TA, Allaby R G, Brown KA, O’Donoghue K, Sallares R (1994) DNA in wheat seeds from European archaeological sites. Experientia 50:571–575CrossRefGoogle Scholar
  16. Budu-Amoako E, Toora S, Ablett RF, Smith J (1993) Competitive growth of Listeria monocytogenes and Yersinia enterocolita in milk. J Food Protection 56:528–532Google Scholar
  17. Burger J, Hummel S, Pfeiffer I, Herrmann B (2000) Palaeogenetic analysis of (pre)historic artifacts and its significance for anthropology. Anthropol Anz 58:69–76Google Scholar
  18. Burger J, Pfeiffer I, Hummel S, Fuchs R, Brenig B, Herrmann B (2001) Mitochondrial and nuclear DNA from (pre)historic hide-derived material. Ancient Biomo13:227–238Google Scholar
  19. Cann RL, Stoneking M, Wilson AC (1987) Mitochondrial DNA and human evolution. Nature 325 :31–36CrossRefGoogle Scholar
  20. Chamberlain JS, Gibbs RA, Ranier JE, Nguyen PN, Caskey CT (1988) Deletion screening of the Duchenne muscular dystrophy locus via multiplex DNA amplification. Nucleic Acids Res 16:11141–11156CrossRefGoogle Scholar
  21. Clayton TM, Whitaker JP, Maguire CN (1995) Identification of bodies from the scene of a mass disaster using DNA amplifiication of short tandem repeat (STR) loci. Forensic Sci Int 76:7–15CrossRefGoogle Scholar
  22. Cooper A (1992) Seabird 12S sequences using feathers from museum specimens. Ancient DNA Newsletter 1/2 : 20–21Google Scholar
  23. Corach D, Sala A, Penacino G, Sotelo A (1995) Mass disasters: rapid molecular screening of human remains by means of short tandem repeats typing. Electrophoresis 16:1617–1623CrossRefGoogle Scholar
  24. Corach D, Sala A, Penacino G, Iannucci N, Bernardi P, Doretti M, Fondebrider L, Ginarte A, Inchaurregui A, Somigliana C, Turner S, and Hagelberg E (1997) Additional approaches to DNA typing of skeletal remains: The search for “missing” persons killed during the last dictatorship in Argentina. Electrophoresis 18:1608–1612CrossRefGoogle Scholar
  25. Cunningham J, Harley EH, O’Ryan CO (1999) Isolation and characterization of microsatellite loci in black rhinoceros (Diceros bicornis). Electrophoresis 20:1778–1780CrossRefGoogle Scholar
  26. Dixon RA, Roberts CA (2001) Modern and ancient scourges: the application of ancient DNA to the analysis of tuberculosis and leprosy from archaeologically derived human remains. Ancient Biomol 3:181–193Google Scholar
  27. Drancourt M, Aboudharam G, Signoli M, Dutour O, Raoult D (1998) Detection of 400-year-old Yersinia pestis DNA in human dental pulp: An approach to the diagnosis of ancient septicemia. Proc Natl Acad Sci USA 95:12637–12640CrossRefGoogle Scholar
  28. Edwards A, Hammond HA, Jin L, Caskey CT, Chakraborty R (1992) Genetic variation at five trimeric and tetrameric tandem repeat loci in four human population groups. Genomics 12:241–253CrossRefGoogle Scholar
  29. Ellegren H (1992) Population genetics of museum birds by hypervariable microsatellite typing of genomic DNA prepared from feathers. Ancient DNA Newsletter 1/2: 10Google Scholar
  30. Faerman M, Kahila G, Smith P, Greenblatt C, Stager L, Filon D, Oppenheim A (1997) DNA analysis reveals the sex of infanticide victims. Nature 385 :212–212CrossRefGoogle Scholar
  31. Forster R, Eberspacher B (1999) E vidence of DNA from epithelial cells of the hand of the suspect found on the tool of the crime. Arch Kriminol 203:45–53Google Scholar
  32. Foster EA, Jobling MA, Taylor PG, Donelly P, de Knijff P, Mieremet R, Zerjal T, Tyler-Smith C (1998) Jefferson fathered slave’s last child. Nature 396:27–28CrossRefGoogle Scholar
  33. Fumagalli L, Moritz C, Taberlet P, Friend JA (1999) Mitochondrial DNA sequence variation within the remnant populations of the endangered numbat (Marsupialia: Myrmecobiidae: Myrmecobius fasciatus). Mol Ecol 8: 1545–1549CrossRefGoogle Scholar
  34. Georgiadis N, Patton J, Western D (1990) DNA and the ivory trade: how genetics can help conserve elephants. Pachyderm 13:45–46Google Scholar
  35. Gerstenberger J, Hummel S, Schultes T, Hack B, Herrmann B (1999) Reconstruction of a historical genealogy by means of STR analysis and Y — haplotyping of ancient DNA. Eur J Hum Genet 7:469–477CrossRefGoogle Scholar
  36. Gill P, Ivanov PL, Kimpton C, Piercy R, Benson N, Tully G, Evett I, Hagelberg E, Sullivan K (1994) Identifiication of the remains of the Romanov family by DNA analysis. Nat Genet 6:130–135CrossRefGoogle Scholar
  37. Ginther C, Issel-Tarver L, King MC (1992) Identifying individuals by sequencing mitochondrial DNA from teeth. Nat Genet 2:135–138CrossRefGoogle Scholar
  38. Goloubinoff P, Pääbo S, Wilson AC (1993) Evolution of maize inferred from sequence diversity of an Adh2 gene segment from archaeological specimens. Proc Natl Acad Sci USA 90:1997–2001CrossRefGoogle Scholar
  39. Goodwin W, Linacre A, Vanzis P (1999) The use of mitochondrial DNA and short tandem repeat typing in the identification of air crash victims. Electrophoresis 20:1707–1711CrossRefGoogle Scholar
  40. Grave GR, Braun MJ (1992) Museums: storehouses of DNA? Science 255:1335–1336Google Scholar
  41. Greenblatt C L (ed) (1998) Digging for pathogens. Ancient emerging diseases — their evolutionary, anthropological and archaeological context. Balaban, RehovotGoogle Scholar
  42. Hagelberg E , Sykes B , Hedges R (1989) A ncient b one D NA a mplified. Nature 342:485–485CrossRefGoogle Scholar
  43. Hamada H, Petrino MG, Kakunaga T (1982) A novel repeated element with Z-DNA forming potential is widely found in evolutionary diverse eukaryote genomes. Proc Natl Acad Sci USA 79:6465–6469CrossRefGoogle Scholar
  44. Hamilton H, Caballero S, Collins AG, Brownell RL (2001) Evolution of river dolphins. Proc R Soc Lond B Biol Sci 268:549–556CrossRefGoogle Scholar
  45. Herrmann B, Hummel, S (1993) Ancient DNA. Recovery and analysis of genetic material from palaeontological, archaeological, museum, medical and forensic specimens. Springer, New YorkGoogle Scholar
  46. Herrmann B , Hummel S (1997) Genetic analysis of past populations byaDNAstudies. Advances in research on DNA polymorphisms. ISFH-Symposium, Tovoshoten, Hakone. pp 33–47Google Scholar
  47. Higuchi R, Bowman B, Freiberger M, Ryder OA, Wilson AC (1984) DNA sequences from the quagga, an extinct member of the horse family. Nature 312:282–284CrossRefGoogle Scholar
  48. Hochmeister M, Haberl J, Borer V, Rudin O, Dirnhofer R (1995) Clarifiication of a break-in theft crime by multiplex PCR analysis of cigarette butts. Arch Kriminol 195:177–183Google Scholar
  49. Hofreiter M, Serre D, Poinar HN, Kuch M, Paabo S (2001) Ancient DNA. Nat Rev Genet. 2: 353–359CrossRefGoogle Scholar
  50. Horn GT, Richards B, Klinger KW (1989) Amplification of a highly polymorphic VNTR segment by the polymerase chain reaction. Nucleic Acids Res 17:2140CrossRefGoogle Scholar
  51. Höss M, Kohn M, Pääbo S (1992) Excrement analysis by PCR. Nature 359:199CrossRefGoogle Scholar
  52. Hsieh HM, Chiang HL, Tsai LC, Lai SY, Huang NE, Linacre A, Lee JC (2001) Cytochrome B gene for species identification of the conservation animals. Forensic Sci Int 122:7–18CrossRefGoogle Scholar
  53. Hübner P, Waiblinger HU, Pietsch K, Brodmann P (2001) Validation of PCR methods for quantitation of genetically modified plants in food. J AOAC Int 84:1855–1864Google Scholar
  54. Hunan Medical College (1980) Study of an ancient cadaver in Mawantui tomb no.1 of the Han dynasty in Changsha. Beijing Ancient Memorial Press, BeijingGoogle Scholar
  55. Immel U-D, Hummel S, Herrmann B (1999) DNA profiiling of orangutan (Pongo pygmaeus) feces to prove descent and identity in wildlife animals. Electrophoresis 20:1768–1770CrossRefGoogle Scholar
  56. Ivanov P, Parsons T, Wadhams M, Holland M, Rhoby R, Weedn V (1996) Mitochondrial DNA variations in the Hessian lineage: heteroplasmy found in Grand Duke of Russia Georgij Romanov endsdisputes over a uthenticity of the remains of Tzar Nicholas II. In: Proceedings of the ISFH, Hakone Symposium on DNA polymorphisms. Toyoshoten, HakoneGoogle Scholar
  57. Jeffreys AJ, Wilson V, Thein SL (1985) Individual-specific “fingerprints” of human DNA. Nature 316:76–79CrossRefGoogle Scholar
  58. Jeffreys AJ, Allen MJ, Hagelberg E, Sonnberg A (1992) Identification of the skeletal remains of Josef Mengele by DNA analysis. Forensic Sci Int 56:65–76CrossRefGoogle Scholar
  59. Jehaes E, Decorte R, Peneau A, Petrie JH, Boiry PA, Gilissen A, Moisan JP, Van den Berghe H, Pascal O, Cassiman JJ (1998) Mitochondrial DNA analysis on remains of a putative son of Louis XVII, King of France and MarieAntoinette. Eur J Hum Genet 6:383–395CrossRefGoogle Scholar
  60. Johnson PH, Olson CB, Goodman M (1985) Isolation and characterization of deoxyribonucleic acid from tissue of the woolly mammoth, Mammuthus primigenius. Comp Biochem Physiol 81:1045–1051Google Scholar
  61. Kimpton C, Fisher D, Watson S, Adams M, Urquhart A, Lygo J, Gill P (1994) Evaluation of an automated DNA profiling system employing multiplex amplification of four tetrameric STR loci. Int J Legal Med 106:302–311CrossRefGoogle Scholar
  62. Kohn M, Knauer F, Stoffela A, Schröder W, Pääbo S (1995) Conservation genetics of the European brown bear — a study using excremental PCR of nuclear and mitochondrial sequences. Mol Ecol 4:95–103CrossRefGoogle Scholar
  63. Krafft AE, Duncan BW, Bijward KE, Taubenberger JK, Lichy JH (1997) Optimization of the isolation and amplifiication of RNA from formalin-fixed, paraffin-embedded tissue: The Armed Forces Institute of Pathology experience and literature review. Mol Diagn 2:217–230CrossRefGoogle Scholar
  64. Krajewski C, Driskell AC, Baverstock PR, Braun MJ (1992) Phylogenetic relationships of the thylacine (Mammalia: Thylacinidae) among dasyuroid marsupials: evidence from cytochrome b DNA. Proc R Soc Lond B 250:19–27CrossRefGoogle Scholar
  65. Krings M, Stone A, Schmitz RW, Krainitzki H, Stoneking M, Pääbo S (1997) Neanderthal DNA sequences and the origin of modern humans. Cell 90:19–30CrossRefGoogle Scholar
  66. Kurosaki K, Matsushita T, Ueda S (1993) Individual DNA identifiication from ancient human remains. Am J Hum Genet 53:638–643Google Scholar
  67. Lai-Goldman M, Lai E, Grody WW (1988) Detection of human immunodeficiency virus (HIV) infection in formalin-fixed, paraffin-embedded tissues by DNA amplifiication. Nucleic Acids Res 16:8191CrossRefGoogle Scholar
  68. Lalueza-Fox C, Bertranpetit J, Alcover JA, Shailer N, Hagelberg E (2000) Mitochondrial DNA from Myotragus b alearicus, an extinct bovid from the Balearic Islands. J Exp Zool 288:56–62CrossRefGoogle Scholar
  69. Landergott U, Holderegger R, Kozlowski G, Schneller JJ (2001) Historical bottlenecks decrease genetic diversity in natural populations of Dryopteris cristata. Heredity 87:344–355CrossRefGoogle Scholar
  70. Lassen C, Hummel S, Herrmann B (1996) PCR-based sex determination in ancient human bones by amplifiication of X- and Y-chromosomal sequences. A comparison. Ancient Biomol 1:25–33Google Scholar
  71. Lassen C, Hummel S, Herrmann B (2000) Molecular sex identification of stillborn and neonate individuals (“Traufkinder”) from the burial site Aegerten. Anthrop Anz 58:1–8Google Scholar
  72. Launhardt K, Epplen C, Epplen JT, Winkler P (1998) Amplification of microsatellites adapted from human systems in faecal DNA of wild Hanuman langurs (Presbytis entellus). Electrophoresis 19:1356–1361CrossRefGoogle Scholar
  73. Lederer T, Betz P, Seidl S (2001) DNA analysis of fiingernail debris using different multiplex systems: a case report. Int J Leaal Med 114:263–266CrossRefGoogle Scholar
  74. Leeton P, Christidis L, Westerman M (1993) Feathers from museum birds skins — a good source of DNA for phylogenetic studies. Condor 95:465–466CrossRefGoogle Scholar
  75. Loreille O, Roumat E, Verneau O, Bouchet F, Hanni C (2001) Ancient DNA from Ascaris: extraction amplification and sequences from eggs collected in coprolites. Int J Parasitol 31:1101–1106CrossRefGoogle Scholar
  76. Lygo JE, Johnson PE, Holdaway DJ, Woodroffe S, Whitaker JP, Clayton TM, Kimpton CP, Gill P (1994) The validation of short tandem repeat (STR) loci for use in forensic casework. Int J Legal Med 107:77–89CrossRefGoogle Scholar
  77. MacHugh DE, Troy CS, McCormick F, Olsaker I, Eythorsdottir E, Bradley DG (1999) Early medieval cattle remains from a Scandinavian settlement in Dublin: genetic analysis and comparison with extant breeds. Phil Trans R Soc Toncl B 354:99–108CrossRefGoogle Scholar
  78. McCusker MR, Parkinson E, Taylor EB (2000) Mitochondrial DNA variation in rainbow trout (Oncorhynchus mykiss) across its native range: testing biogeographical hypotheses and their relevance to conservation. Mol Ecol 9:2089–2108CrossRefGoogle Scholar
  79. McKusick VA (1991) Advisory statement by the panel on DNA testing of Abraham Lincoln’s tissue. Caduceus 7:43–47Google Scholar
  80. Meyer R, Höfelein C, Lüthy J, Candrian U (1995) Polymerase chain-reaction restriction fragment length polymorphism analysis: a simple method for species identification in food. J AOAC Int 78:1542–1551Google Scholar
  81. Micozzi MS (1991) When the patient is Abraham Lincoln. Caduceus 7:34–42Google Scholar
  82. Mizuno T, Nagamura H, Iwamoto KS, Ito T, Fukuhara T, Tokunaga M, Tokuoka S, Mabuchi K, Seyama T (1998) RNA from decades-old archival tissue hincks for retrospective studies. Diagn Mol Pathol 7:202–208CrossRefGoogle Scholar
  83. Moura SM, Destro MT, Franco BDGM (1993) Incidence of Listeria species in raw and pasteurized milk produced in Sao Paulo, Brazil. Int J Food Microbiol 19:229–237CrossRefGoogle Scholar
  84. Mullis KB, Faloona FA (1987) Specific synthesis of DNA in vitro via a polymerase-catalysed chain reaction. Meth Enzymol 155:335–350CrossRefGoogle Scholar
  85. Nyakaana S, Arctander P (1999) Population genetic structure of the African elephant in Uganda based on variation at mitochondrial and nuclear loci: evidence for male-biased gene flow. Mol Ecol 8:1105–1115CrossRefGoogle Scholar
  86. Ohnishi Y, Tanaka T, Ozaki K, Yamada R, Suzuki H, Nakamura Y (2001) A high-throughput SNP typing system for genome-wide association studies. J Hum Genet 46:471–477CrossRefGoogle Scholar
  87. Ovchinnikov IV, Gotherstrom A, Romanova GP, Kharitonov VM, Lidén K, Goodwin W (2000) Molecular analysis of Neanderthal DNA from the northern Caucasus. Nature 404:490–493CrossRefGoogle Scholar
  88. Pääbo S (1984) Über den Nachweis von DNA in altägyptischen Mumien. Das Altertum 30:213–218Google Scholar
  89. Pääbo S, Wilson AC (1991) Miocene DNA sequences — a dream come true? Curr Biol 1:45–46CrossRefGoogle Scholar
  90. Paxinos EE, James HF, Olson SL, Sorensen MD, Jackson J, Fleischer RC (2002) mtDNA from fossils reveals a radiation of Hawaiian g eese recently derived from the Canada goose (Branta canadensis). Proc Natl Acad Sci USA 99:1399–1404CrossRefGoogle Scholar
  91. Persing DH, Telford SR, Rys PN, Dodge DE, White TJ, Malawista SE, Spielman A (1990) Detection of Borrelia burgdorferi DNA in museums pecimens of Ixodes dammini ticks. Science 249:1420–1423CrossRefGoogle Scholar
  92. Pertoldi C, Hansen MM, Loeschke V, Madsen AB, Jacobsen L, Baagoe H (2001) Genetic consequences of population decline in the European otter (Lutra lutra): an assessment of microsatellite DNA variation in Danish otters from 1883–1993. Proc R Soc Bio Sci 268:1775–1785CrossRefGoogle Scholar
  93. Plath A, Krause I, Einspanier R (1997) Species identifiication in dairy products by three different DNA-based techniques. Z Lebensm Unters Forsch 205:437–441CrossRefGoogle Scholar
  94. Poinar HN, Kuch M, Sobolik KD, Barnes I, Stankiewicz AB, Kuder T, Spaulding WG, Bryant VM, Cooper A, Paabo S (2001) A molecular analysis of dietary diversity for three archaic Native Americans. Proc Natl Acad Sci USA 98:4317–4322CrossRefGoogle Scholar
  95. Rafi A, Spigelman M, Stanford J, Lemma E, Donoghue H, Zias J (1994) Mycobacterium leprae DNA from ancient bone detected by PCR. Lancet 343:1360–1361CrossRefGoogle Scholar
  96. Ramos MD, Lalueza C, Girbau E, Pérez-Pérez A, Quevedo S, Turbón D, Estivill X (1995) Amplifying dinucleotide microsatellite loci from bone and tooth samples of up to 5,000 years of age: more inconsistency than usefullness. Hum Genet 96:205–212CrossRefGoogle Scholar
  97. Raoult D, Aboudharam G, Crubezy E, Larrouy G, Ludes B, Drancourt M (2000) Molecular identifiication by “suicide PCR” of Yersinia pestis as the agent of medieval black death. Proc Natl Acad Sci USA 97:12800–12803CrossRefGoogle Scholar
  98. Rogers S O, Bendich AJ (1985) Extraction of DNA from milligram a mounts of fresh, herbarium and mummifiied plant tissues. Plant Mol Biol 5:69–76CrossRefGoogle Scholar
  99. Rollo F, Asci W, Antonini S, Marota I, Ubaldi M (1994) Molecular ecology of a Neolithic meadow: the DNA of the grass remains from the archaeological site of the Tyrolean iceman. Experientia 50:576–584CrossRefGoogle Scholar
  100. Rosenbaum HC, Egan MG, Clapham PJ, Brownell RLJ, DeSalle R (1997) An effective method for isolating DNA from historical specimens of baleen. Mol Eco 16:677–681CrossRefGoogle Scholar
  101. Roy MS, Girman DJ, Taylor AC, Wayne RK (1994) The use of museum specimens to reconstruct the genetic variability and relationships of extinct populations. Experientia 50:551–557CrossRefGoogle Scholar
  102. Saiki RK, Scharf S, Faloona F, Mullis KB, Horn GT, Erlich HA, Arnheim N (1985) Enzymatic amplification of P-globulin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science 230:1350–1354CrossRefGoogle Scholar
  103. Salo WL, Aufderheide AC, Buikstra J, Holcomb TA (1994) Identification of Mycobacterium tuberculosis in a pre-Columbian Peruvian mummy. Proc Natl Acad Sci USA 91:2091–2094CrossRefGoogle Scholar
  104. Schlumbaum A, Neuhaus JM, Jacomet S (1998) Coexistence of tetraploid and hexaploid naked wheat in a Neolithic lake dwelling of central Europe. Evidence from morphology and ancient DNA. J Archaeol Sci 25:1111–1118CrossRefGoogle Scholar
  105. Schneider H, Neuhuber F (1996) Detection of saliva traces on perpetrator masks and their attribution to a particular criminal. Arch Kriminol 198:31–37Google Scholar
  106. Schneider PM, Seo Y, Rittner C (1999) Forensic mtDNA hair analysis excludes a dog from having caused a traffiic accident. Int J Legal Med 112:315–316CrossRefGoogle Scholar
  107. Scholz M, Hengst S, Broghammer M, Pusch CM (2001) Intrapopulational relationships in ancient societies: a multidisciplinary study. Z Morph Anthrop 83:5–21Google Scholar
  108. Schultes T, Hummel S, Herrmann B (1999) Amplification of Y-chromosomal STRs from ancient skeletal material. Hum Genet 104:164–166CrossRefGoogle Scholar
  109. Schultes T (2000) Typisierung alter DNA zur Rekonstruktion von Verwandtschaft in einem bronzezeitlichen Skelettkollektiv. Dissertation, Georg AugustUniversität, Göttingen. Cuvellier, GöttingenGoogle Scholar
  110. Siragusa GR, Nawotka K, Spilman SD, Contag PR, Contag CH (1999) Real-time monitoring of Escherichia coli 0157:H7 adherence to beef carcass surface tissues with a bioluminiscent reporter. Appl Environ Microbiol 65:1738–1745Google Scholar
  111. Smith KM, Crandall KA, Kneissl ML, Navia BA (2000) PCR detection of host and HIV-1 sequences from archival brain tissue. J Neurovirol 6:164–171CrossRefGoogle Scholar
  112. Sorenson MD, Cooper A, Paxinos EE, Quinn TW, James HF, Olson SL, Fleischer RC (1999) Relationships of the extinct moa-nalos, flightless Hawaiian waterfowl, based on ancient DNA. Proc R Soc Lond B Biol Sci 266:2187–2193CrossRefGoogle Scholar
  113. Spencer PB, Odorico DM, Jones SJ, Marsh HD, Miller DJ (1995) Highly variable microsatellites in isolated colonies of the rock-wallaby (Petrogale assimilis). Mol Ecol 4:523–525CrossRefGoogle Scholar
  114. Spencer PB, Bryant KA (2000) Characterization of highly polymorphic microsatellite markers in the marsupial honey possum (Tarsipes rostratus). Mol Ecol 9:492–494CrossRefGoogle Scholar
  115. Spigelman M, Lemma E (1993) The use of the polymerase chain reaction to detect Mycobacterium tuberculosis in ancient skeletons. Int J Osteoarchaeol 3:137–143CrossRefGoogle Scholar
  116. Stone AC, Milner GR, Pääbo S, Stoneking M (1996) Sex determination of ancient human skeletons using DNA. Am J Phys Anthropo 199:231–238CrossRefGoogle Scholar
  117. Stone AC, Starrs JE, Stoneking M (2001) Mitochondrial DNA analysis of the presumptive remains of Jesse James. J Forensic Sci 46:173–176Google Scholar
  118. Stoneking M, Melton T, Nott J, Baritt S, Roby R, Holland M, Weedn V, Gill P, Kimpton C, Aliston G (1995) Establishing the identity of Anna Anderson Manahan. Nat Genet 9:9–10CrossRefGoogle Scholar
  119. Su B, Wang Y, Lan H, Wang W, Zhang Y (1999) Phylogenetic study of complete cytochrome B genes in musk deer (Genus Moschus) using museum samples. Mol Phylogen Evol 12:241–249CrossRefGoogle Scholar
  120. Taillon-Miller P, Piernot EE, Kwok PY (1999) Efficient approach to unique single-nucleotide polymorphism discovery. Genome Res 9:499–505Google Scholar
  121. Teuber M(1993) Genetic engineering techniques in food microbiology and enzymology. Food Rev Int 9:389–409CrossRefGoogle Scholar
  122. Thomas RH (1994) Analysis of DNA from natural history museum collections. In: Schierwater B, Streit B, Wagner GP, DeSalle R (eds) Molecular ecology and evolution: Approaches and applications. Birkhäuser, Basel. pp 311–321Google Scholar
  123. Troy CS, MacHugh DE, Bailey JF, Magee DA, Loftus RT, Cunningham P, Chamberlain AT, Sykes BC, Bradley DG (2001) Genetic evidence for NearEastern origins of European cattle. Nature 410:1088–1091CrossRefGoogle Scholar
  124. Urquhart A, Oldroyd NJ, Kimpton CP, Gill P (1995) Highly discriminating heptaplex short tandem repeat PCR system for forensic identifiication. BioTechniques 18:116–121Google Scholar
  125. Verma SK, Khanna V, Singh N (1999) Random amplified polymorphic DNA analysis of Indian scented basmati rice (Oryza sativa L.) germplasm for identification of variability and duplicate accession, if any. Electrophoresis 20:1786–1789CrossRefGoogle Scholar
  126. Vernesi C, Caramelli D, Carbonelli Sala S, Ubaldi M, Rollo F, Chiarelli B (1999) Application of DNA sex tests to bone specimens from three Etruscan archaeological sites. Ancient Biomol 2:295–305Google Scholar
  127. Vernesi C, Di Benedetto G, Caramelli D, Secchieri E, Simoni L, Katti E, Malaspina P, Novelletto A, Marin VT, Barbujani G (2001) Genetic characterization of the body attributed to the evangelist Luke. Proc Natl Acad Sci USA 98:13460–13463CrossRefGoogle Scholar
  128. Vila C, Leonard JA, Gotherstrom A, Marklund S, Sandberg K, Liden K, Wayne RK, Ellegren H (2001) Widespread origins of domestic horse lineages. Science 291:474–477CrossRefGoogle Scholar
  129. Wang DG, Fan JB, Siao CJ, Berno A, Young P, Sapolsky R, Ghandour G, Perkins N, Winchester E, Spencer J, Kruglyak L, Stein L, Hsie L, Topaloglou T, Hubbell E, Robinson E, Mittmann M, Morris MS, Shen N, Kilburn D, Rioux J, Nusbaum C, Rozen S, Hudson TJ, Lander ES (1998) Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome. Science 280:1077–1082CrossRefGoogle Scholar
  130. Weichhold GM, Bark JE, Korte W, Eisenmenger W, Sullivan KM (1998) DNA analysis in the case of Kasper Hauser. Int J Legal Med 111:287–291CrossRefGoogle Scholar
  131. Whitaker JP, Clayton TM, Urquhart AJ, Millican ES, Downes TJ, Kimpton CP, Gill P (1995) Short tandem repeat typing of bodies from a mass disaster: high success rate and characteristic amplification patterns in highly degraded samples. BioTechniques 18:670–677Google Scholar
  132. Wolf C, Burgener M, Hübner P, Lüthy J (2000) PCR-RFLP analysis of mitochondrial DNA: differentiation of fish species. Lebensm Wiss Technol 33:144–150CrossRefGoogle Scholar
  133. Woodward B (1999) Shadow: Five presidents and the legacy of Watergate. Simon and Schuster, New YorkGoogle Scholar
  134. Yang H, Golenberg EM, Shoshani J (1997) A blind testing design for authenticating ancient DNA sequences. Mol Phylogenet Evo 17:261–265CrossRefGoogle Scholar
  135. Zawko G, Krauss SL, Dixon KW, Sivasithamparam K (2001) Conservation genetics of the rare and endangered Leucopogon obtectus (Ericaceae). Mol Ecol 10:2389–2396CrossRefGoogle Scholar
  136. Zierdt H, Hummel S, Herrmann B (1996) Amplification of human short tandem repeats from medieval teeth and bone samples. Hum Bio 168:185–199Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • Susanne Hummel
    • 1
  1. 1.Historische Anthropologie und Humanökologie, Institut für Zoologie und AnthropologieGeorg August Universität GöttingenGöttingenGermany

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