Electrocorticographic Coherence Patterns of Epileptic Seizures
One of the most difficult questions facing epileptologists involved in the surgical treatment of epilepsy is the identification of brain areas that are responsible for event initiation, or that participate in the propagation of seizures. Determining the initial location and extent of the epileptogenic focus and the spatio-temporal organization of the neural populations causing seizures are crucial for the successful surgical treatment of intractable epilepsy, and for the treatment of patients with lesional brain processes accompanied by epileptic seizures. The practical problem of epilepsy surgery — that of determining the limits of a cortical resection that will prevent the recurrence of epileptic seizures, is only partially resolved. The decision of whether to resect or leave a marginally active area of cortex intact elicits a wide range of opinions from clinicians. Advances in neuro-surgical and imaging techniques have increased the proportion of intractable epilepsy patients that can be successfully treated with surgery. Many of the expensive hospital days spent in monitoring units are spent waiting to record seizures so that these areas can be identified. If such areas could be more easily identified during the interictal period, the length and costs of epilepsy work-ups could be dramatically reduced. Further, if such areas could be identified more precisely, the efficacy of seizure surgery would be increased.
KeywordsEpileptic Seizure Superior Temporal Gyrus Spontaneous Seizure Colour Plate Direct Cortical Stimulation
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