Periplasmic Space and Rigid Layer

  • Guntram Seltmann
  • Otto Holst
Chapter

Abstract

The region between cytoplasmic and outer membrane of the Gram-negative bacteria is called the periplasmic space. It contains a concentrated gel-like matrix, the periplasm. Embedded in it is a rigid layer (peptidoglycan). Its width has been electron microscopically determined as 13–25 nm, a variation range that may be explained by differences in cultivation or preparation conditions. The total volume of the periplasmic space has been determined as 20–40% of the whole cell; this value, however, is not identical with that calculated from the width, which would allow a volume of only 8–16%. Because of its great importance for the vital processes of the bacteria, the existence of a space at least similar to the periplasmic is also thought to be present in Gram-positive bacteria (Dijkstra and Keck 1996).

Keywords

Glycine Polysaccharide Chitin Vancomycin NADP 

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Copyright information

© Springer-Verlag Berlin Heidelberg 2002

Authors and Affiliations

  • Guntram Seltmann
    • 1
  • Otto Holst
    • 2
  1. 1.WernigerodeGermany
  2. 2.Zentrum für Medizin und BiowissenschaftenForschungszentrum BorstelBorstelGermany

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