Abstract
Our knowledge of the “outside” world is to a large extent dependent on our five senses. Taste and aroma are two of these that, initially at least, humans and other animals were dependent on for their very survival. Now of course they also hold the key to our enjoyment of life as well. Recently, several research teams have reported on the molecular biology of receptors for taste (Hoon et al. 1999) and aroma (Malnic et al. 1999), which has potential for explaining some of the known characteristics of these two senses, and for predicting other unsuspected properties.
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References
Avenet P, Hofmann F, Lindemann B (1988) Transduction taste receptor cells requires cAMP-dependent protein kinase. Nature 331:351–354
Brown EM, Gamba G, Riccardi D, Lomardi M, Butlers R, Kifor O, Sun A, Hediger MA, Lytton J, Herbert SC (1993) Cloning and characterization of an extracellular Ca2+-sensing receptor from bovine parathyroid. Nature 366:575–580
Buck L (1996) Information coding in the vertebrate olfactory system. Annu Rev Neurosci 19: 517–544
Buck L, Axel R (1991) A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. Cell 65:175–187
Cain WS (1988) Olfaction. In: Atkinson RJ, Hermstein RJ, Lindzey G, Luce RD (eds) Steven’s handbook of experimental psychology — perception and motivation. Wiley, New York, pp 409–459
Gilbertson TA, Avenet P, Kinnamon SC, Roper SD (1992) Proton currents through amiloridesensitive Na channels in hamster taste cells. Role in acid transduction. J Gen Physiol 100: 803–824
Heck GL, Mierson S, DeSimone JA (1984) Salt taste transduction occurs through an amiloridesensitive sodium transport pathway. Science 223:403–405
Heck MA, Adler E, Lindereier J, Battery JF, Ryba NJP, Zuker CS (1999) Putative mammalian taste receptors: a class of taste-specific GPCRs with distinct topographic selectivity. Cell 96: 541–551
Hoon MA, Ryba NJP (1997) Analysis and comparison of partial sequences of clones from a taste-bud-enriched cDNA library. J Dent Res 76:831–838
Hoon MA, Adler E, Lindemeier J, Battery JF, Ryba NJP, Zuker CS (1999) Putative mammalian taste receptors: a class of taste-specific GPCRs with distinct topographic selectivity. Cell 96: 541–551
Kinnamon SC, Dionne VE, Beam KG (1988) Apical localization of K+ channels in taste cells provides the basis for sour taste transduction. Proc Natl Acad Sci USA 85:7023–7027
Lindemann B (1996) Taste reception. Physiol Rev 76:718–760
Malnic B, Hirono J, Sato T, Buck LB (1999) Combinational receptor codes for odors. Cell 96: 713–723
Mombaerts P, Wang F, Dulac C, Chao S, Nemes A, Mendelsohn M, Edmondson J, Axel R (1996) Visualizing an olfactory sensory map. Cell 87:675–686
Nakanishi S (1992) Molecular diversity of glutamate receptors and implications for brain function. Science 258:597–603
Ryba NJP, Tirindelli R (1997) A new multigene family of putative pheromone receptors. Neuron 19:371–379
Shepherd GM (1988) Neurobiology. Oxford University Press, New York
Spielman AI, Huque T, Whitney G, Brand JG (1992) The diversity of bitter taste signal transduction mechanisms. Soc Gen Physiol Ser 47:307–324
Troemel ER, Chou JH, Dwyer ND, Colbert HA, Bargmann CI (1995) Divergent seven transmembrane receptors are candidate chemosensory receptors in C. elegans. Cell 83:207–218
Wong GT, Gannon KS, Margolskee RF (1996) Transduction of bitter and sweet taste by gustducin. Nature 381:796–800
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Jackson, J.F. (2002). Molecular Biology of Taste and Aroma Receptors: Implications for Taste and Aroma of Plant Products. In: Jackson, J.F., Linskens, H.F. (eds) Analysis of Taste and Aroma. Molecular Methods of Plant Analysis, vol 21. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-04857-3_1
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DOI: https://doi.org/10.1007/978-3-662-04857-3_1
Publisher Name: Springer, Berlin, Heidelberg
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