A-Current Diversity: Differences in Channel Hardware or Second Messengers?
The pyloric network generates a rhythmic motor behavior that is continuously adaptive (Harris-Warrick et al. 1992). This patterned activity is based not only on synaptic connectivity, but also on the unique firing properties of the component neurons. There are many molecular devices that could establish different firing properties between neurons, ranging from relatively static mechanisms like differential gene expression, to more dynamic methods such as changes in ion channel phosphorylation states. The strategies involved most likely reflect elementary principles of the system. Defining these strategies for the pyloric network could provide insights into its dynamic nature.
KeywordsVoltage Dependence Somatodendritic Compartment Shaker Channel Pyloric Network Transient Potassium Current
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