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Name Reactions pp 269-269 | Cite as

Passerini reaction

  • Jie Jack Li

Abstract

Three-component condensation (3CC) of carboxylic acids, C-isocyanides, and oxo compounds to afford α-acyloxycarboxamides. Cf. Ugi reaction.

Keywords

Inorganic Chemistry Organic Chemistry Carboxylic Acid Organic Synthesis Acyl Transfer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Passerini, M. Gazz. Chim. Ital. 1921, 51, 126, 181.Google Scholar
  2. 2.
    Ferosie, I. Aldrichimica Acta 1971, 4, 21.Google Scholar
  3. 3.
    Ugi, I.; Lohberger, S.; Karl, R. In Comprehensive Organic Synthesis, Trost, B. M.; Fleming, I., Eds, Pergamon: Oxford, 1991, Vol. 2, p. 1083.Google Scholar
  4. 4.
    Ziegler, T.; Kaisers, H.-J.; Schlomer, R.; Koch, C. Tetrahedron 1999, 55, 8397.CrossRefGoogle Scholar
  5. 5.
    Banfi, L.; Guanti, G.; Riva, R. Chem. Commun. 2000, 985.Google Scholar
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    Semple, J. E.; Owens, T. D.; Nguyen, K.; Levy, O. E. Org . Lett. 2000, 2, 2769.CrossRefGoogle Scholar
  7. 7.
    Owens, T. D.; Semple, J. E. Org . Lett. 2001, 3, 3301.CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2002

Authors and Affiliations

  • Jie Jack Li
    • 1
  1. 1.Chemistry DepartmentPfizer Global Research and DevelopmentAnn ArborUSA

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