Name Reactions pp 204-204 | Cite as

Krapcho decarboxylation

  • Jie Jack Li


Nucleophilic decarboxylation of β-ketoesters, malonate esters, α-cyanoesters, and α-sulfonylesters.


Inorganic Chemistry Organic Chemistry Malonate Ester 
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  1. 1.
    Krapcho, A. P.; Glynn, G. A.; Grenon, B. J. Tetrahedron Lett. 1967, 215.Google Scholar
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    Flynn, D. L.; Becker, D. P.; Nosal, R.; Zabrowski, D. L. ibid 1992, 33, 7283.Google Scholar
  3. 3.
    Martin, C. J.; Rawson, D. J.; Williams, J. M. J. Tetrahedron: Asymmetry 1998, 9, 3723.CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2002

Authors and Affiliations

  • Jie Jack Li
    • 1
  1. 1.Chemistry DepartmentPfizer Global Research and DevelopmentAnn ArborUSA

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