Idiopathic Inflammatory Myopathies
We recognize today two main diseases of the skeletal musculature which have an autoimmune causation. Myasthenia gravis is characterized by a reversible fatigue of the musculature; its etiology is concerned with the formation of antibodies to acetylcholine receptors. This non-inflammatory process is in contrast to a heterogenous group of diseases which are included in the term “idiopathic inflammatory myopathies”(IIM). These are dermatomyositis (DM), polymyositis (PM), and inclusion body myositis (IBM). Clinically, they are all characterized by muscle weakness, histologically by inflammatory reactions in the muscle.
KeywordsMuscle Weakness Inclusion Body Myositis Mixed Connective Tissue Disease Idiopathic Inflammatory Myopathy Fibre Degeneration
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