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Topical Glucocorticoid Therapy in Dermatology

  • Conference paper
Recent Advances in Glucocorticoid Receptor Action

Part of the book series: Ernst Schering Research Foundation Workshop ((SCHERING FOUND,volume 40))

Abstract

In dermatology, glucocorticoids (GCs) are the most widely used drugs. Systemic, intralesional, and in particular topical applications are the daily practice of the dermatologist. Table l gives examples of frequent indications. Since cutaneous (topical) GC therapy is the domain of dermatologists, this will be within the focus of this review.

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References

  • Alani MD, Alani SD (1972) Allergic contact dermatitis to corticosteroids. Ann Allergol 30: 181–185

    CAS  Google Scholar 

  • Amin S, Maibach HI, Cornell RC, Stoughton RB (1998) Topical corticoids. In: Roenigk Jr HH, Maibach HI (eds) Psoriasis, 3rd edn. Marcel Dekker, New York, pp 453–467

    Google Scholar 

  • Arbiser JL, Grossman K, Kaye E, Arndt KA (1994) Use of short-course class I topical glucocorticoid under occlusion for the rapid control of erythrodermic psoriasis. Arch Dermatol 130: 704–706

    Article  PubMed  CAS  Google Scholar 

  • Baker H (1976) Corticosteroids and pustular psoriasis. Br J Dermatol 94 [Suppl 121: 83–88

    Article  Google Scholar 

  • Charman CR, Morris AD, Williams HC (2000) Topical corticosteroid phobia in patients with atopic eczema. Br J Dermatol 142: 931–936

    Article  PubMed  CAS  Google Scholar 

  • Cornell RC, Stoughton RB (1985) Correlation of the vasoconstrictor assay and clinical activity in psoriasis. Arch Dermatol 121: 63–67

    Article  PubMed  CAS  Google Scholar 

  • Cubey RB (1976) Glaucoma following the application of corticosteroids to the skin of the eyelids. Br J Dermatol 95: 207–208

    Article  PubMed  CAS  Google Scholar 

  • Freiwel M (1969) Percutaneous absorption of topical steroids in children. Br J Dermatol 81 [Suppl4]: 113–116

    Article  Google Scholar 

  • Glade CP, van Erp PEJ, van de Kerkhof PCM (1996) Epidermal cell DNA content and intermediate filaments keratin 10 and vimentin after treatment of psoriasis with calcipotriol cream once daily, twice daily and in combination with clobetasone 17-butyrate cream or betamethasone 17-valerate cream: a comparative low cytometric study. Br J Dermatol 135: 379–384

    Article  PubMed  CAS  Google Scholar 

  • Gomez EC, Kaminester L, Frost P (1977) Topical halcinonide and betamethasone valerate effects on plasma cortisol. Arch Dermatol 113: 1196–1202

    Article  PubMed  CAS  Google Scholar 

  • Gould PW, Wilson L (1977) Psoriasis treated with clobetasol propionate and photochemotherapy. Br J Dermatol 98: 133–136

    Article  Google Scholar 

  • Higgins EM, DuVivier A (1994) Glucocorticosteroids. In: Dubertret L (ed) Psoriasis. ISED, Brescia, pp 102–111

    Google Scholar 

  • Katz HI, Prawer RS, Krueger GG, Mooney JJ, Jones ML, Samson CR (1991) Intermittent corticosteroid maintenance treatment of psoriasis: a double blind multicenter trial of augmented betamethasone dipropionate ointment in a pulse dose treatment regimen. Dermatologica 183: 269–274

    Article  PubMed  CAS  Google Scholar 

  • Lebwohl M, Abel E, Zanolli M, Koo J, Drake L (1995) Topical therapy for psoriasis. Int J Dermatol 44: 673–684

    Google Scholar 

  • Lee SW, Morhenn VB, Ilnicka M, Eugui EM, Allison A (1991) Autocrine stimulation of interleukin-lalpha and transforming growth factor alpha production in human keratinocytes and its antagonism by GCs. J Invest Dermatol 97: 106–110

    Article  PubMed  CAS  Google Scholar 

  • MacKenzie AW, Stoughton RB (1962) Method for comparing percutaneous absorption of steroids. Arch Dermatol 86: 608–610

    Article  Google Scholar 

  • Maibach HI, Surber C (1992) Topical corticosteroids. Karger, Basel

    Google Scholar 

  • Meola T, Soter NA, Lim HW (1991) Are topical corticosteroids useful adjunctive therapy for the treatment of psoriasis with ultraviolet radiation? Br J Dermatol 127: 1708–1713

    Article  Google Scholar 

  • Rasmussen E (1986) Psoriasis in children. Dermatol Clin 4: 99–106

    Article  PubMed  CAS  Google Scholar 

  • Ruzicka T, Lorenz B (1998) Comparison of calcipotriol monotherapy and a combination of calcipotriol and betamethasone valerate after 2 weeks’ treatment with calcipotriol in the topical therapy of psoriasis vulgaris: a multicentre, double-blind, randomized study. Br J Dermatol 138: 254–258

    Article  PubMed  CAS  Google Scholar 

  • Schmoll M, Henseler T, Christophers E (1978) Evaluation of PUVA, topical corticosteroids and the combination of both in the treatment of psoriasis. Br J Dermatol 99: 693–702

    Article  PubMed  CAS  Google Scholar 

  • Singh S (1996) Augmented betamethasone: efficacy in psoriasis with different dosing frequencies. Arch Dermatol 132: 1525–1526

    Article  PubMed  CAS  Google Scholar 

  • Stern RS (1996) Utilization of outpatient care for psoriasis. J Am Acad Dermatol 35: 543–545

    Article  Google Scholar 

  • Sterry W (1992) Therapy with topical corticosteroids. Arch Dermatol Res 284 [Suppl 11: 27–29

    Article  Google Scholar 

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© 2002 Springer-Verlag Berlin Heidelberg

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Sterry, W., Asadullah, K. (2002). Topical Glucocorticoid Therapy in Dermatology. In: Cato, A.C.B., Schäcke, H., Asadullah, K. (eds) Recent Advances in Glucocorticoid Receptor Action. Ernst Schering Research Foundation Workshop, vol 40. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-04660-9_3

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  • DOI: https://doi.org/10.1007/978-3-662-04660-9_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-04662-3

  • Online ISBN: 978-3-662-04660-9

  • eBook Packages: Springer Book Archive

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