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Analysis of Glucocorticoid Receptor Function in the Mouse by Gene Targeting

  • Conference paper
Recent Advances in Glucocorticoid Receptor Action

Part of the book series: Ernst Schering Research Foundation Workshop ((SCHERING FOUND,volume 40))

  • 132 Accesses

Abstract

Glucocorticoids, produced in the adrenal cortex, play an important role in a variety of organ systems during development and in many physiological and pathological processes (Miller and Blake Tyrrel 1995). The glucocorticoid receptor (GR) mediates the effects of glucocorticoids by positively or negatively influencing gene activity. Glucocorticoid-controlled functions range from the regulation of metabolism, the stress response and control of innate and acquired immunity to modulation of behaviour.

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Authors
  1. C. Kellendonk
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  2. F. Tronche
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  3. H. M. Reichardt
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  4. A. Bauer
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  5. E. Greiner
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  6. W. Schmid
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  7. G. Schütz
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Editor information

Editors and Affiliations

  1. Institute of Toxicology and Genetics, Forschungszentrum Karlsruhe, P.O. Box 3640, 76021, Karlsruhe, Germany

    A. C. B. Cato

  2. Research Business Area Dermatology, Schering AG, Müllerstr. 178, 13342, Berlin, Germany

    H. Schäcke  & K. Asadullah  & 

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© 2002 Springer-Verlag Berlin Heidelberg

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Kellendonk, C. et al. (2002). Analysis of Glucocorticoid Receptor Function in the Mouse by Gene Targeting. In: Cato, A.C.B., Schäcke, H., Asadullah, K. (eds) Recent Advances in Glucocorticoid Receptor Action. Ernst Schering Research Foundation Workshop, vol 40. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-04660-9_17

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  • DOI: https://doi.org/10.1007/978-3-662-04660-9_17

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-04662-3

  • Online ISBN: 978-3-662-04660-9

  • eBook Packages: Springer Book Archive

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