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Phototherapy and Photochemotherapy of the Idiopathic Photodermatoses

  • Adrian Tanew
  • James Ferguson

Abstract

The term idiopathic photodermatoses denotes dermatological diseases that occur in otherwise healthy individuals as a result of exposure to natural or artificial light without the intervention of an external photosensitizer. This group of diseases includes polymorphic light eruption, hydroa vacciniforme, actinic prurigo, solar urticaria, and chronic actinic dermatitis. All these diseases have two factors in common: first, they are precipitated by electromagnetic radiation in the ultraviolet or visible range; second, the exact pathomechanism leading to the clinical manifestation of these diseases remains to be elucidated, but presumably it is immunologic in nature. In particular, it is still entirely unknown which chromophore(s) are responsible for the initiation of the photochemical reactions that ultimately lead to the inflammatory reaction in the skin. Diagnosis of the photodermatoses is mainly based on clinical features and phototesting, whereas histopathological or laboratory investigations play a subordinate role.

Keywords

PUVA Treatment Polymorphic Light Eruption Solar Urticaria Light Eruption Chronic Actinic Dermatitis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2001

Authors and Affiliations

  • Adrian Tanew
  • James Ferguson

There are no affiliations available

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