Andrology pp 177-189 | Cite as

Diseases of the Seminal Ducts

  • H. M. Behre
  • E. Nieschlag
  • D. Meschede


Infections of the seminal ducts can lead to male infertility by different mechanisms. Direct damage is caused by microorganisms or their secretory products, while secondary inflammation is produced by increased numbers of activated lenkocytes and an elevated secretion of lymphokines and and monokines. In addition, increased formation of reactive oxygen species (ROS) can reduce the fertilization capacity of the spermatozoa (De Geyter et al. 1994; Comhaire et al. 1999; Weidner et al. 1999). Infections can also lead to uni- or bilateral obstructions of the seminal ducts, formation of antibodies against sperm and dysfunction of ejaculation (Purvis and Christiansen 1993; WHO 1999; Pasehke et al. 1994a). Furthermore, an acute epididymitis can lead to infection of the testis (epididymoorchitis).


Cystic Fibrosis Seminal Plasma Infertile Couple Ejaculatory Duct Ureaplasma Urealyticum 
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© Springer-Verlag Berlin Heidelberg 2001

Authors and Affiliations

  • H. M. Behre
  • E. Nieschlag
  • D. Meschede

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