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Actinobacillus actinomycetemcomitans: Electrotransformation of a Periodontopathogen

  • Keith P. Mintz
  • Paula Fives-Taylor
Chapter
Part of the Springer Lab Manuals book series (SLM)

Abstract

Periodontal diseases are chronic inflammatory conditions of the subgingival epithelium that have bacterial etiologies. Actinobacillus actinomycetemcomitans, a gram-negative, capnophilic coccobacillus, has been implicated in the pathogenesis of juvenile and adult periodontitis. This bacterium elaborates a number of virulence factors that may contribute to the disease process. Molecular analysis is crucial to understanding the precise role of these and other bacterial factors.

Keywords

Chronic Inflammatory Condition Bacterial Pellet Bacterial Etiology Electroporation Cuvette Public Health Service Grant 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Sreenivasan PK, LeBlanc DJ, Lee LN and Fives-Taylor PM (1991) Transformation of Actinobacillus actinomycetemcomitans by electroporation, utilizing constructed shuttle plasmids. Infect Immun 59: 4621–4627Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2000

Authors and Affiliations

  • Keith P. Mintz
    • 1
  • Paula Fives-Taylor
    • 1
  1. 1.Department of Microbiology and Molecular Genetics, The Markey Center for Molecular Genetics, College of Medicine and College of Agriculture and Life SciencesUniversity of VermontBurlingtonUSA

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