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Organofluorine Building Blocks

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Book cover Organofluorine Compounds

Abstract

The synthetic methodology for organofluorine compounds is generally classified into two approaches: one involves C-F bond formation via transformation of a suitable functional group by a fluorinating reagent, as described in Chap. 2, and the other includes C-C bond formation starting from a relatively small fluorine-substituted molecule which is readily available and can be easily handled. This approach is called the building block approach and is familiar to synthetic chemists, because hazardous and toxic reagents and special equipment are not necessary. This chapter focuses on the synthetic transformation of fluorine-containing building blocks in the order of the type of reagent.

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Authors and Affiliations

  1. Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Yoshida, Sakyo-ku, 606-8501, Kyoto, Japan

    Professor Tamejiro Hiyama

  2. Graduate School of Engineering, Nagoya University, Chikusa, 464-8603, Nagoya, Japan

    Professor Hisashi Yamamoto

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  1. Professor Tamejiro Hiyama
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  2. Professor Hisashi Yamamoto
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  1. Graduate School of Engineering, Nagoya University, Chikusa, 464-8603, Nagoya, Japan

    Hisashi Yamamoto

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Hiyama, T., Yamamoto, H. (2000). Organofluorine Building Blocks. In: Yamamoto, H. (eds) Organofluorine Compounds. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-04164-2_3

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