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Normal Anatomy and Histology

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Bone Diseases

Abstract

A variety of lesions can arise in any bone, or in different parts of the same bone, bringing about destruction or at least an alteration of the normal structure of the tissue. Depending upon their severity, these changes may be recognizable on a radiograph. The ability to assess a pathological lesion of bone naturally requires exact knowledge of the normal structure. At the macroscopic level, the distinction between the different types of bone change is first and foremost a matter of radiology, and it is by this means that the first examination is always carried out. The conventional radiograph, which is usually taken in two planes, provides the earliest and most conclusive information. The diagnostic value of such a radiograph is primarily dependent upon its quality.

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References

  • Adler CP (1981) Störungen der Funktion des Knochens. In: Sandritter W (ed) Allgemeine Pathologie, 2nd edn. Schattauer, Stuttgart, pp 717–740

    Google Scholar 

  • Adler CP (1987) Die Bedeutung von mehrkernigen Riesenzellen in Knochentumoren und tumorähnlichen Läsionen. Verh Dtsch Ges Pathol 71:366

    Google Scholar 

  • Adler CP (1992) Knochen — Gelenke. In: Thomas C (ed) Histopathologic, 11th edn. Schattauer, Stuttgart, pp 290–314

    Google Scholar 

  • Adler CP (1992) Knochen und Gelenke. In: Thomas C (ed) Grundlagen der klinischen Medizin. Schattauer, Stuttgart

    Google Scholar 

  • Adler CP (1993) Knochen und Gelenke. In: Thomas C (ed) Makropathologie, 8th edn. Schattauer, Stuttgart, pp 147–171

    Google Scholar 

  • Adler CP (1996) Knochen — Knorpel. In: Thomas C (ed) Spezielle Pathologie. Schattauer, Stuttgart, pp 527–593

    Google Scholar 

  • Adler CP, Klümper A (1977) Röntgenologische und pathologisch-anatomische Aspekte von Knochentumoren. Radiologe 17:355–392

    PubMed  CAS  Google Scholar 

  • Adler CP, Klümper A, Hosemann W (1983) Intraossäre Angiographie von Knochentumoren. Radiologe 23:128–136

    PubMed  CAS  Google Scholar 

  • Amato VP, Bombelli R (1959) The normal vascular supply of the vertebral colunin in the growing rabbit. J Bone Joint Surg Br 41:782–795

    PubMed  Google Scholar 

  • Amling M, Delling G (1997) Differenzierung und Funktion des Osteoklasten — Neue Ergebnisse und Modellvorstellungen. Osteologie 6:4–14

    Google Scholar 

  • Anderson DW (1960) Studies of the lymphatic pathways of bone and bone marrow. J Bone Joint Surg Am 42:716

    Google Scholar 

  • Anderson HC (1989) Mechanism of mineral formation in bone. Lab Invest 60:320–330

    PubMed  CAS  Google Scholar 

  • Anseroff NJ (1934) Die Arterien der langen Knochen des Menschen. Z Anat Entwickl Gesch 103:793–812

    Article  Google Scholar 

  • Bargmann W (1977) Histologie und mikroskopische Anatomie des Menschen, 7th edn. Thieme, Stuttgart

    Google Scholar 

  • Brookes M (1958 a) The vascular architecture of tubular bone in the rat. Anat Rec 132:25–47

    Article  PubMed  CAS  Google Scholar 

  • Brookes M (1958 b) The vascularization of long bones in the human foetus. J Anat (Lond) 92:261–267

    CAS  Google Scholar 

  • Brookes M (1963) Cortical vascularization and growth in foetal tubular bones. J Anat (Lond) 97:597–609

    CAS  Google Scholar 

  • Brookes M (1967) The osseous circulation. Biomed Eng 2:294–299

    Google Scholar 

  • Brookes M (1971) The blood supply of bone. An approach to bone biology. Butterworth, London

    Google Scholar 

  • Burkhardt R (1992) Der Osteoblast — Schlüssel zum Verständnis des Skelettorgans. Osteologie 1:139–170

    Google Scholar 

  • Cameron DA (1963) The fine structure of bone and calcified cartilage. A critical review of the contribution of electron microscopy to the understanding of osteogenesis. Clin Orthop 26:199–228

    PubMed  CAS  Google Scholar 

  • Cohen J, Harris WH (1958) The three dimensional anatomy of Haversian systems. J Bone Joint Surg 40:419–434

    PubMed  Google Scholar 

  • Crock HV (1967) The blood supply of the lower limb bones in man. Livingstone, London

    Google Scholar 

  • Cumming D (1962) A study of blood flow through bone marrow by a method of venous effluent collection. J Physiol (Lond) 162:13–20

    CAS  Google Scholar 

  • Fischer H (1980) Mechanische Beanspruchung und biologisches Verhalten des Knochens. In: Staubesand J (ed) Lehrbuch der Anatomie des Menschen. Makroskopische und mikroskopische Anatomie unter funktionellen Gesichtspunkten, vol 1, 13th edn. Urban & Schwarzenberg, Munich

    Google Scholar 

  • Frost HM (1960) In vivo staining of bone with tetracyclines. Stain Technol 35:135–138

    PubMed  CAS  Google Scholar 

  • Frost HM (1963) Bone remodelling dynamics. Thomas, Springfield, 111.

    Google Scholar 

  • Garden RS (1961) The structure and function of the proximal end of the femur. J Bone Joint Surg 43:576–589

    Google Scholar 

  • Goldhaber P (1962) Some current concepts of bone physiology. N Engl J Med 266:924–931

    Article  PubMed  CAS  Google Scholar 

  • Gurley AM, Roth SL (1992) Bone. In: Sternberg SS (ed) Histology for pathologists, chap 3. Raven, New York, pp 61–79

    Google Scholar 

  • Hancox N (1956) The osteoclast. In: Bourne GH (ed) The biochemistry and physiology of bone. Academic Press, New York

    Google Scholar 

  • Hert J, Hladikov AJ (1961) Die Gefäßversorgung des Haversschen Knochens. Acta Anat (Basel) 45:344–361

    Article  CAS  Google Scholar 

  • Heuck F (1979) Radiologie des gesunden Skelettes. In: Schinz HR, Baensch WE, Frommhold W et al (eds) Lehrbuch der Röntgendiagnostik, vol Il/part 1, 6th edn. Thieme, Stuttgart, pp 3–143

    Google Scholar 

  • Howe WW, Lacey T, Schwartz RP (1950) A study of the gross anatomy of the arteries supplying the proximal portion of the femur and the acetabulum. J Bone Joint Surg Am 32:856–866

    PubMed  Google Scholar 

  • Jaffe HL (1929) The vessel canals in normal and pathological bone. Am J Pathol 5:323–333

    PubMed  CAS  Google Scholar 

  • Junqueira LC, Carneiro J (1996) Histologie — Zytologie Histologie und mikroskopische Anatomie des Menschen, 4th edn. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Johnson RW (1927) A physiological study of the blood supply of the diaphysis. J Bone Joint Surg 9:153–184

    Google Scholar 

  • Judet J, Judet R, Lagrange J, Dunoyer J (1955) A study of the arterial vascularization of the femoral neck in the adult. J Bone Joint Surg Am 37:663–680

    PubMed  Google Scholar 

  • Kelly PJ, Janes JM, Peterson LFA (1959) The effect of arteriovenous fistulae on the vascular pattern of the femora of immature dogs: a micro-angiographic study. J Bone Joint Surg Am 41:1101–1108

    Google Scholar 

  • Klümper A(1969) Intraossäre Angiographic Topographische und morphologische Untersuchungen zur Darstellung intraossärer Gefäße. Habilitationsschrift, Universität Freiburg

    Google Scholar 

  • Klümper A (1976) Möglichkeiten der intraossären Angiographie zur Differentialdiagnose von Knochentumoren. Orthop Prax 10:949–953

    Google Scholar 

  • Klümper A (1976) Grundlagen zur intraossären Angiographie am menschlichen Röhrenknochen. Fortschr Rönt-genstr 125:129–136

    Article  Google Scholar 

  • Klümper A (1977) Differentialdiagnose aneurysmatische Knochenzyste und nicht ossifizierendes Fibrom. Fortschr Röntgenstr 127:261–264

    Article  Google Scholar 

  • Klümper A, Strey M, Schütz W (1968) Tierexperimentelle Untersuchungen zur intraossären Angiographie. Fortschr Röntgenstr 108:607–612

    Article  Google Scholar 

  • Lewis OJ (1956) The blood supply of developing long bones with special reference to the metaphysis. J Bone Joint Surg Br 38:928–933

    PubMed  Google Scholar 

  • Pauwels F (1973) Atlas zur Biomechanik der gesunden und kranken Hüfte. Prinzip, Technik und Resultate einer kausalen Therapie. Springer, Berlin Heidelberg New York

    Book  Google Scholar 

  • Pliess G (1974) Bewegungsapparat. In: Doerr W (ed) Organpathologie, vol 111. Thieme, Stuttgart

    Google Scholar 

  • Pommer G (1927) Über Begriff und Bedeutung der durchbohrenden Knochenkanäle. Z Mikrosk Anat Forsch 9:540–584

    Google Scholar 

  • Pritchard JJ (1956) The osteoblast. In: Bourne GH (ed) The biochemistry and physiology of bone. Academic Press, New York

    Google Scholar 

  • Rauber A, Kopsch F (1968) Lehrbuch und Atlas der Anatomie des Menschen, vol 1, 20th edn. Thieme, Stuttgart

    Google Scholar 

  • Resch H, Battmarm A (1995) Die Bedeutung von Wachstumsfaktoren und Zytokinen im Knochenstoffwechsel und Remodeling. Osteologie 4:137–144

    Google Scholar 

  • Rogers WM, Gladstone H (1950) Vascular foramina and arterial supply of the distal end of the femur. J Bone Joint Surg Am 32:867–974

    PubMed  CAS  Google Scholar 

  • Schinz HR, Baensch WE, Friedl E, Uehlinger E (1952) Lehrbuch der Röntgendiagnostik, 5th edn. Thieme, Stuttgart

    Google Scholar 

  • Schumacher S (1935) Zur Anordming der Gefäßkanäle in der Diaphyse langer Röhrenknochen des Menschen. Z Mikrosk Anat Forsch 38:145–160

    Google Scholar 

  • Tilling G (1958) The vascular anatomy of long bones: a radiological and histological study. Acta Radiol (Stockh) 1–107

    Google Scholar 

  • Wilkinson LS, Pitsillides AA, Worrall JG, Edwards JCW (1992) Light microscopic characterization of the fibroblast-like synovial intimai cell (synoviocyte). Arthritis Rheum 35:1179–1184

    Article  PubMed  CAS  Google Scholar 

  • Zheng MH, Wood DJ, Papadimitriou JM (1992) What’s new in the role of cytokines on osteoblast proliferation and differentiation? Pathol Res Pract 188:1104–1121

    Article  PubMed  CAS  Google Scholar 

Download references

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Adler, CP. (2000). Normal Anatomy and Histology. In: Bone Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-04088-1_2

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  • DOI: https://doi.org/10.1007/978-3-662-04088-1_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-08450-8

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