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Tools for Drug Discovery: Natural Product-based Libraries

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Book cover The Role of Natural Products in Drug Discovery

Part of the book series: Ernst Schering Research Foundation Workshop ((SCHERING FOUND,volume 32))

Abstract

About 30% of the drugs sold worldwide are based on natural products. Though recombinant proteins and peptides account for an increasing market volume, the superiority of low-molecular-mass compounds in human disease therapy remains undisputed, due mainly to more favorable compliance and bioavailability properties. In the past, new therapeutic approaches have often evolved from research involving natural products. Numerous examples from medicine impressively demonstrate the innovative potential of natural compounds and their impact on progress in drug discovery and development. However, natural products are currently undergoing a phase of reduced attention because of the enormous effort which is necessary to isolate the active principles and to elucidate their chemical structures.

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Authors
  1. S. Grabley
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  2. R. Thiericke
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  3. I. Sattler
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Editor information

Editors and Affiliations

  1. Institut für Organische Chemie, Universität Wien, Währinger Str. 38, 1090, Wien, Austria

    J. Mulzer

  2. Preclinical Drug Research, Schering AG, Müllerstr. 178, 13342, Berlin, Germany

    R. Bohlmann

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Grabley, S., Thiericke, R., Sattler, I. (2000). Tools for Drug Discovery: Natural Product-based Libraries. In: Mulzer, J., Bohlmann, R. (eds) The Role of Natural Products in Drug Discovery. Ernst Schering Research Foundation Workshop, vol 32. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-04042-3_8

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  • DOI: https://doi.org/10.1007/978-3-662-04042-3_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-04044-7

  • Online ISBN: 978-3-662-04042-3

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