Abstract
It is well established that estrogen replacement therapy (ERT) or hormone replacement therapy (HRT) is effective not only for improving menopausal symptoms, but also for preventing osteoporosis and cardiovascular disease in postmenopausal women (Belchetz 1994). Furthermore, estrogen does influence brain function, but the effects of estrogen on brain function such as memory, cognitive function, and brain blood flow have not been well established in postmenopausal women or female patients with dementia of the Alzheimer type (DAT). Our studies will to some extent clarify the clinical aspects of HRT and brain function. Based on our data, this paper will report the effects of HRT on brain function in postmenopausal women and DAT patients. Our studies are divided into three parts: 1. Estrogen and Memory (Sect. 5.1), 2. Estrogen and Brain Blood Flow (Sect. 5.2), and 3. HRT for Dementia of the Alzheimer Type (DAT) (Sect. 5.3).
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Ohkura, T., Isse, K., Tanaka, K., Akazawa, K., Hamamoto, M., Iwasaki, N. (2000). HRT and Brain Function — Clinical Aspects. In: Kato, J., Minaguchi, H., Nishino, Y. (eds) Hormone Replacement Therapy and Osteoporosis. Ernst Schering Research Foundation Workshop, vol 4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-04021-8_5
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DOI: https://doi.org/10.1007/978-3-662-04021-8_5
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