Abstract
This chapter reports the first resolution of a folding pathway of a protein (barstar, the 10 kDa polypeptide inhibitor of the ribonuclease barnase, see Fig. 10.1) from a well-characterized unfolded state (Sect. 10.4) at the level of individual amino acid residues on a microsecond to second time scale. The presentation, which is largely based on several articles by the author and coworkers (Nölting et al., 1995, 1997a, b; Nölting, 1996, 1998a, b, 1999), is intended to illustrate the method of Φ-value analysis (see Sect. 8.3) in detail and in a more applied way than in the previous chapters.
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© 1999 Springer-Verlag Berlin Heidelberg
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Nölting, B. (1999). The folding pathway of a protein (barstar) at the resolution of individual residues from microseconds to seconds. In: Protein Folding Kinetics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-03966-3_10
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DOI: https://doi.org/10.1007/978-3-662-03966-3_10
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-03968-7
Online ISBN: 978-3-662-03966-3
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