Advertisement

Antiphospholipid Syndrome

  • P. G. Vlachoyiannopoulos
  • H. M. Moutsopoulos

Abstract

Antiphospholipid (anticardiolipin) syndrome (APS) is a chronic disorder associated with recurrent venous and/or arterial thrombosis, recurrent abortions, thrombocytopenia and/or autoimmune hemolytic anemia and positive results are obtained from tests for antiphospholipid antibodies (aPL) and/or lupus anticoagulant (LA). The disease can occur alone (primary APS) or in association with other systemic autoimmune diseases, especially systemic lupus erythematosus (SLE), (secondary APS).

Synonym

Anticardiolipin Syndrome 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Haris EN (1997) “Management of the antiphospholipid syndrome. In: van de Putte LBA, Furst DE, Williams H), van Riel PLCM (eds) Therapy of systemic rheumatic disorders. Marcel Dekker, New York 33:629–656Google Scholar
  2. 2.
    Rosove MH, Brewer PMC (1992) Antiphospholipid thrombosis: clinical course after the first thrombotic event in 70 patients. Ann Intern Med 17: 303–308CrossRefGoogle Scholar
  3. 3.
    Sturtelt G, Mousa F, Jonsson H et al. (1990) Recurrent cerebral infarction and the antiphospholipid syndrome: effect of intravenous gammaglobulin in a patient with systemic lupus erythematosous. Ann Rheum Dis 49: 939–941CrossRefGoogle Scholar
  4. 4.
    Roach BA, Hutchinson GJ (1993) Treatment of refractory, systemic lupus erythematosus–associated thrombocytopenia with intermittent low dose intravenous cyclophosphamide. Artritis Rheum 36: 682–684CrossRefGoogle Scholar
  5. 5.
    Laskin CA, Bombardier C, Hannah M et al. (1997) Prednisone and aspirin in women with autoantibodies and unexplained recurrent fetal loss. N Engl J Med 337: 148–152PubMedCrossRefGoogle Scholar
  6. 6.
    Vlachoyiannopoulos PG, Tsiakou E, Chalevelakis G, Raptis SA, Moutsopoulos HM (1993) Antiphospolipid syndrome: Clinical and therapeutic aspects. Lupus 3: 91–96CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2000

Authors and Affiliations

  • P. G. Vlachoyiannopoulos
  • H. M. Moutsopoulos

There are no affiliations available

Personalised recommendations