Glucocorticoids Systemic

  • J. G. Camarasa
  • A. Giménez-Arnau


Glucocorticoids are used routinely in the management of skin diseases, due to their potent anti-inflammatory and immunosuppressive actions. The following summarizes the general concept that physicians have about the use of steroids.


Adrenal Insufficiency Pyoderma Gangrenosum Bullous Pemphigoid Erythema Multiforme Chronic Idiopathic Urticaria 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Reynolds JEF, Parfitt K, Parsons AV, Sweetman SC 1993 ) Corticosterois. MARTINDALE the Extra Pharmacopoeia. 30 Edición. The Pharmaceutical Press, London, pp 712–740Google Scholar
  2. 2.
    Murray JR (1989) The history of corticosteroids. Acta Derm Venereol 69 [Suppl 1511: 4–6Google Scholar
  3. 3.
    Werth VP, Lazarus GS (1993) Systemic glucocorticosterids. In: Fitzpatrick TB, Eisen A, Wolff K, Freedberg IM, Austen KF (eds) Dermatology in general medecine. Fourth edition. McGraw-Hill, pp 2859–2864Google Scholar
  4. 4.
    Markham A, Bryson HM (1995) Deflazacort. A review of its pharmacological properties and therapeutic efficacy. Drugs 50: 317–333Google Scholar
  5. 5.
    Blackwell GJ, Carnuccio R, Di Rosa M, Flower RJ, Parente L, Persico P (1980) Macrocortin: A polypeptide causing the anti-phospholipase effect of glucocorticoids. Nature 287: 147–149Google Scholar
  6. 6.
    Hammarström S, Hamberg M, Duell EA, Stawiski MA, Anderson TF,Voorhees JJ (1977) Glucocorticoid in inflammatory proliferative skin disease reduces arachidonic and hydroxyeicosatetraenoic acids. Science 197: 994–995Google Scholar
  7. 7.
    Brattsand R, Linden M (1996) Cytokine modulation by glucocorticoids: mechanisms and actions in cellular studies. Aliment Pharmacol Ther 10 [Suppl 21: 81–90Google Scholar
  8. 8.
    Krueger GG, Emam M (1984) Biology of Langerhans cells:Analysis by experiments to deplete Langerhans cells from human skin. J Invest dermatol 82: 613–617PubMedCrossRefGoogle Scholar
  9. 9.
    Paradis L, Lavoie A, Brunet C, Bedart PM, Hebert J (1996) Effects of systemic corticosteroids on cutaneous histamine secretion and histamine-releasing factor in patients with chronic idiopathic urticaria. Clin Exp Allergy 26: 815–820PubMedCrossRefGoogle Scholar
  10. 10.
    Brattsand R, Sarnstrand B (1989) Prospects for future topical glucocorticoid development. Acta Derm Venereol 69 [Suppl 1511: 37–46Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2000

Authors and Affiliations

  • J. G. Camarasa
  • A. Giménez-Arnau

There are no affiliations available

Personalised recommendations