A Search for a Mechanism for the Antiinflammatory Action of Glucocorticoids

  • A. C. B. Cato
Conference paper
Part of the Ernst Schering Research Foundation Workshop book series (SCHERING FOUND, volume 24)


Cortisol, a glucocorticoid hormone, was first isolated from adrenal tissues in 1936 (Mason et al. 1936a,b) and about 10 years later it was shown to be effective in the treatment of rheumatoid arthritis, particularly when administered pharmacologically (Hench et al. 1949, 1950).


Glucocorticoid Receptor Antiinflammatory Action Secretory Leukocyte Protease Inhibitor Chemokine Gene High Mobility Group Protein 
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