Abstract
Primordial germ cells (PGCs) are the founder cells of germ line. In all mammalian species studied, including humans, they originate extragonadally during early embryogenesis before moving toward and colonizing the gonadal ridges. Upon entering the gonads, PGCs differentiate into meiotic oocytes in the fetal ovary and prospermatogonia in the fetal testis.
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De Felici, M., Di Carlo, A., Dolci, S., Pesce, M. (1998). Experimental In Vitro Approaches to the Study of Mouse Primordial Germ Cell Development. In: Stefanini, M., Boitani, C., Galdieri, M., Geremia, R., Palombi, F. (eds) Testicular Function: From Gene Expression to Genetic Manipulation. Ernst Schering Research Foundation Workshop, vol 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-03671-6_2
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DOI: https://doi.org/10.1007/978-3-662-03671-6_2
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