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Regulation of Virulence by Endogenous Signal Molecules and the Importance of Extracellular Polysaccharide During Infection and Colonization

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Bacterial Wilt Disease

Abstract

Expression of some virulence genes controlled by the global regulator PhcA increases >20-fold during exponential growth of R. solanacearum. These cell density-associated changes suggest that autoregulators may control a shift between low and high virulence phenotypes. Virulence genes are not regulated by acyl homoserine lactones; however, a novel fatty acid autoregulator is essential for normal virulence gene expression. Acidic extracellular polysaccharide increases bacterial pathogenic/reproductive fitness, since it is required for rapid systemic colonization of tomato plants.

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© 1998 Springer-Verlag Berlin Heidelberg

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Denny, T.P., Flavier, A.B., Clough, S.J., Saile, E., Ganova-Raeva, L.M., Schell, M.A. (1998). Regulation of Virulence by Endogenous Signal Molecules and the Importance of Extracellular Polysaccharide During Infection and Colonization. In: Prior, P., Allen, C., Elphinstone, J. (eds) Bacterial Wilt Disease. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-03592-4_24

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  • DOI: https://doi.org/10.1007/978-3-662-03592-4_24

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-08361-7

  • Online ISBN: 978-3-662-03592-4

  • eBook Packages: Springer Book Archive

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