Regulation of RNA Polymerase III Transcription

  • Robert J. White
Part of the Biotechnology Intelligence Unit book series (BIOIU)


There are two families of active 5S genes in Xenopus laevis. One consists of the somatic 5S genes, of which there are 400 copies per haploid genome, organized in a single cluster.1,2 The other is divided into two classes, the 20,000 major oocyte and the 1,30o trace oocyte 5S genes.3,4 There are only 6 nucleotides different between the 120 bp coding regions of the somatic and major oocyte types, but the flanking sequences are completely divergent.1,3,4


Xenopus Laevis tRNA Gene Silk Gland Immature Oocyte Mitotic Extract 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1998

Authors and Affiliations

  • Robert J. White
    • 1
  1. 1.Institute of Biomedical and Life Sciences Division of Biochemistry and Molecular BiologyUniversity of GlasgowGlasgowScotland, UK

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