Abstract
Animal cell culture began in 1912 when Alexis Carrel grew bits of chick heart in vitro by placing them into a drop of horse plasma. When the plasma clotted, it formed a solid surface into which the heart cells explanted. Left unattended, these cells died within several days. By regularly feeding the growing cells with aqueous extracts of whole chick embryos and periodically subdividing them, Carrel was able to maintain the cells for extended periods. From these initial experiments, cell culture has expanded into an important component of biological research and commercial production.
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References
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© 1997 Springer-Verlag Berlin Heidelberg
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Gooch, K.J., Tennant, C.J. (1997). Introduction. In: Gooch, K.J., Tennant, C.J. (eds) Mechanical Forces: Their Effects on Cells and Tissues. Biotechnology Intelligence Unit. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-03420-0_1
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DOI: https://doi.org/10.1007/978-3-662-03420-0_1
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