Evidence-Based Andrology: The Importance of Controlled Clinical Trials

  • E. Leifke
  • E. Nieschlag
Conference paper
Part of the Ernst Schering Research Foundation Workshop book series (SCHERING FOUND, volume 2/1996)

Abstract

The concept of evidence-based medicine has emerged over the past decades, and, by virtue of its pervasive influence, is becoming a “constitutional amendment” in all fields of clinical practice. Personal authority and skills born of experience are no longer the major determining factors when therapeutic decisions must be made. In addition to pathophysiological rationales and professional expertise, clinical practice should be based on properly designed studies and applied statistics, summarized under the term of outcome research (Evidence-Based Medicine Working Group 1992). While widely regarded as an oddity in medicine up to the 1960s, today the controlled, prospective, randomized — and if possible — double-blind clinical trial is accepted as the most reliable method of proving the effectiveness of diagnostic and therapeutic strategies. No drug, no surgical therapy, and not even a diagnostic test should enter or remain in clinical practice without evidence and outcome research-based confirmation of their benefits.

Keywords

Placebo Estrogen Testosterone Tamoxifen Glucocorticoid 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1996

Authors and Affiliations

  • E. Leifke
  • E. Nieschlag

There are no affiliations available

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