Biochemical Assessment of Bone Metabolism in Rodents

  • Roman C. Mühlbauer
Part of the Ernst Schering Research Foundation Workshop book series (SCHERING FOUND, volume 9)


This is not an exhaustive review of biochemical methods to assess bone resorption and bone formation in rats and mice but is complementary to the subjects presented by the other contributors to this volume. A number of methods are discussed which have proven to be powerful research tools, mostly in our institution, and have led, for example, to the clinical development of several bisphosphonates. These should also be useful tools for establishing the efficacy of analogs of sex steroids as agents to prevent and possibly cure bone loss.


Bone Resorption Inhibit Bone Resorption Biochemical Assessment Stimulate Bone Resorption Bone Resorp 
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© Springer-Verlag Berlin Heidelberg 1994

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  • Roman C. Mühlbauer

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