Techniques for Studying Blood Platelet Adhesion

  • J. J. Sixma
  • P. G. de Groot

Abstract

Adhesion of blood platelets to the vessel wall is the first step in the formation of a haemostatic plug or thrombus. Because of this, it is an important and crucial step. Routine techniques for the study of platelet function do not include adhesion studies, partly because no reliable technique is available. Information about adhesive function is sought by indirect means such as aggregation of blood platelets caused by collagen or studies of the von Willebrand factor- Glycoprotein lb interaction via the use of the obsolete antibiotic ristocetin or the snake venom protein botrocetin.

Keywords

Catheter Depression Urea Aspirin Prostaglandin 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1994

Authors and Affiliations

  • J. J. Sixma
  • P. G. de Groot

There are no affiliations available

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