Adaptins and their Role in Clathrin-Mediated Vesicle Sorting
Adaptins are subunits of protein complexes known as adaptors, which are components of the coats on clathrin-coated vesicles. Several lines of evidence support the model shown in Figure 1, in which the adaptors are depicted as the components of the coats that give coated pits and vesicles their specificity, enabling them to concentrate selected membrane proteins which act as receptors for ligands on the other side of the membrane.
KeywordsCoat Protein Coated Vesicle Golgi Membrane Peripheral Membrane Protein Cell BioI
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