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Membrane Protein Structure Determination by Deuterium-NMR Case Study: Retinal in Bacteriorhodopsin

  • Anne S. Ulrich
  • Anthony Watts
Conference paper
Part of the NATO ASI Series book series (volume 63)

Abstract

To understand the function of a protein, one needs to establish the relationship between its three-dimensional structure, its dynamics and its environment. For many soluble proteins the primary, secondary and tertiary structures have been described in considerable detail, but a crucial gap in our knowledge is still the molecular structure of membrane proteins. These cannot usually be investigated by diffraction methods, because their amphipathic nature makes crystallization inherently difficult.

Keywords

Nuclear Magnetic Resonance Quadrupole Splitting Purple Membrane Extracellular Side Thermal Isomerization 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • Anne S. Ulrich
    • 1
  • Anthony Watts
    • 1
  1. 1.Department of BiochemistryUniversity of OxfordOxfordEngland

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