Lipid Modifications of Proteins

  • Milton J. Schlesinger
Part of the NATO ASI Series book series (volume 63)


A protein’s structure and function is determined by both its primary amino acid sequence and by covalent modifications of these amino acids. Among the very large number of such alterations, which can vary from simple inorganic substituents to complex arrays of oligosaccharides, are a group of lipids. The latter have been detected in many proteins that associate with cellular membranes and in a variety of virus structural polypeptides. Thus far, four distinct types of lipid modifications have been identified in eukaryotic cell and virus proteins (Fig. 1).


Myristic Acid Vesicular Stomatitis Virus Virus Assembly Rous Sarcoma Virus Sindbis Virus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • Milton J. Schlesinger
    • 1
  1. 1.Department of Molecular MicrobiologyWashington University School of MedicineSt.LouisUSA

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