The tooth germ has three main components — the enamel organ, the dental papilla and the dental follicle (Fig. 1). The enamel organ is an epithelial structure derived from the ectoderm that lines much of the oral cavity. The dental papilla and the dental follicle are ectomesenchymal (mesectodermal), being partly derived from cells that migrated from the neural crest early in embryogenesis. Both the gross morphology of the tooth germ and the differentiation of its cells depend upon a complex pattern of inductive interactions between the epithelium and the ectomesenchyme.
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Notes on Terminology
- 1.Where there is good evidence that a lesion is neoplastic, this will be stated in the brief definition of the lesion that precedes the detailed description.Google Scholar
- 2.Where there is good evidence that a lesion represents a developmental anomaly or malformation, this will also be stated in the brief definition.Google Scholar
- 3.In accordance with common practice, the terms `lesion’ and ‘lesional tissue’ will be used for both neoplastic and non-neoplastic disorders.Google Scholar
- 4.Synonyms are given where they have been widely used in the literature; the preferred term is given first, followed by the synonym in brackets.Google Scholar