Abstract
Family studies have shown a greater risk for schizophrenia in the close relatives of schizophrenics than is to be expected in the general population. Investigations of twins have revealed much higher concordance figures for monozygotic than for dizygotic twins with respect to schizophrenia. However, several twin studies also clearly show that the clinical picture of the nonschizophrenic monozygotic cotwin is variable, ranging from a duplication of the schizophrenic psychosis to neurosis, or even clinical normality (Kringlen 1987).
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References
Alanen YO, Rekola JK, Stewen A, Takala K, Tuovinen M (1966) The family in the pathogenesis of schizophrenic and neurotic disorders. Acta Psychiatr Scand Suppl 189
Eaves LJ (1984) The resolution of genotypexenvironment interaction in segrekation analysis of nuclear families. Genet Epidemiol 1: 215–228
Goldstein MJ, Strachan AM (1987) The family and schizophrenia. In: Jacob T (ed) Goldstein MJ, Strachan AM, pp 481–508 ( Applied clinical psychology series )
Heston LL (1966) Psychiatric disorders in foster home reared children of schizophrenic mothers. Br J Psychiatry 112: 819–825
Kendler KS, Eaves LJ (1986) Models for the joint effect of genotype and environment on liability to psychiatric illness. Am J Psychiatry 143: 279–289
Kendler KS, Gruenberg AM (1984) An independent analysis of the Danish Adoption Study of schizophrenia. VI. The relationship between psychiatric disorders as defined by DSM-III in the relatives and adoptees. Arch Gen Psychiatry 41: 555–564
Kety SS, Rosenthal D, Wender PH, Schulsinger (1975) Mental illness in the biological and adoptive families of adoptive individuals who have become schizophrenic: a preliminary report based on psychiatric interviews. In: Fieve RR, Rosenthal D, Brill H (eds) Genetic research in psychiatry. Johns Hopkins University Press, Baltimore, pp 147–165
Kety SS, Rosenthal D, Wender PH, Schulsinger F, Jacobsen B (1978) The biologic and adoptive families of adopted individuals who became schizophrenic: prevalence of mental illness and other characteristics. In: Wynne LC, Cromwell RL, Matthysse S (eds) The nature of schizophrenia. Wiley, New York, pp 25–37
Kinney DK, Jacobsen B (1981) Environmental factors elucidated by adoption studies. In: Perris C, Struwe G, Jansson B (eds) Biological psychiatry 1981. Elsevier, Amsterdam, pp 89–92
Kringlen E (1987) Contributions of genetic studies on schizophrenia. In: Häfner H, Gattaz WF, Janzarik W (eds) Search for the causes of schizophrenia. Springer, Berlin Heidelberg New York, pp 123–142
Lowing PA, Mirsky AF, Pereira R (1983) The inheritance of schizophrenia spectrum disorders: a reanalysis of the Danish Adoptee Study data. Am J Psychiatry 140: 1167–1171
Rosenthal D, Wender PH, Kety SS, Welner J, Schulsinger F (1971) The adopted-away offspring of schizophrenics. Am J Psychiatry 128: 307–311
Rosenthal D, Wender PH, Kety SS, Schulsinger F, Weiner J, Rieder RO (1975) Parent-child rela- tionships and psychopathological disorder in the child. Arch Gen Psychiatry 32: 466–476
Tienari P, Lahti I, Sorri A, Naarala M, Wahlberg K-E, Rönkkö T, Moring J, Wynne LC (1987a) The Finnish Adoptive Family Study of Schizophrenia: possible joint effects of genetic vulnerability and family interaction. In: Hahlweg K, Goldstein MJ (eds) Understanding major mental disorder. Family Process Press, New York, pp 33–54
Tienari P, Sorri A, Lahti I, Naarala M, Wahlberg K-E, Moring J, Pohjola J, Wynne LC (1987b) Genetic and psychosocial factors in schizophrenia: the Finnish Adoptive Family Study. Schizophr Bull 13: 477–484
Tienari P, Lahti I, Sorri A, Naarala M, Moring J, Wahlberg K-E, Wynne LC (1987c) The Finnish Adoptive Family Study of Schizophrenia. J Psychiatr Res 21: 437–445
Tienari P, Lahti I, Sorri A, Naarala M, Moring J, Wahlberg K-E (1989) The Finnish Adoptive Family Study of Schizophrenia: possible joint effects of genetic vulnerability and family environment. Br J Psychiatry [Suppl 5]155: 29–32
Tienari P, Lahti I, Sorri A, Naarala M, Moring J, Kaleva M, Wahlberg K-E, Wynne LC (1990) Adopted-away offspring of schizophrenics and controls: the Finnish Adoptive Family Study of Schizophrenia. In: Robins L, Rutter M (eds) Straight and devious pathways from childhood to adulthood Cambridge University Press, New York, pp 365–379
Wender PH, Rosenthal D, Kety SS (1968) A psychiatric assessment of the adoptive parents of schizophrenics. In: Rosenthal D, Kety SS (eds) The transmission of schizophrenia. Pergamon, Oxford, pp 235–250
Wender PH, Rosenthal D, Kety SS, Schulsinger D, Welner J (1973) Social class and psychopathology in adoptees. Arch Gen Psychiatry 28: 318–325
Wender PH, Rosenthal D, Kety SS et al. (1974) Crossfostering: a research strategy for clarifying the role of genetics and experimental factors in the etiology of schizophrenia. Arch Gen Psychiatry 30: 121–128
Wynne LC, Singer MT, Toohey ML (1976) Communication of the adoptive parents of schizophrenics. In: Jorstad J, Ugelstad E (eds) Schizophrenia 75. Universitetsforlaget, Oslo, pp 413 —451
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Tienari, P. et al. (1991). Adoption Studies on Schizophrenia. In: Eggers, C. (eds) Schizophrenia and Youth. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-02684-7_5
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DOI: https://doi.org/10.1007/978-3-662-02684-7_5
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