Vascular Reactivity in Atopic Eczema

  • T. J. Ryan


The term “atopy” describes the altered reactivity characteristic of asthma, hayfever and eczema. These are common problems tending to run in families, and especially affecting children. The principal manifestations involving the lung, nose or skin have attracted an enormous volume of literature. That the blood vessels play some part in the mechanisms underlying the disorder is clear, especially in the congested and oedematous nasal mucosa of hayfever and the urticarial response and vasodilation in eczema, but less obviously so in asthma. Infact, urticaria was a prominant feature in 11% of children in one large French study [78]. The contribution of a raised surface temperature to itch is also important in the skin.


Mast Cell Atopic Eczema Contact Dermatitis Histamine Release Fibrinolytic Enzyme 
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