IgG Subclasses in Atopic Eczema

  • R. C. Aalberse

Abstract

Atopic eczema (AE) is often accompanied by abnormalities in the humoral immune system. Most striking in this respect is often a marked increase in IgE production. However, abnormalities are also found regularly in other immunoglobulin isotypes, particularly IgG1 and IgG4. Before I review the data on IgG antibody levels in AE it might be useful to provide some background information on the humoral immune system in general and on the immunoglobulin isotype switch in particular.

Keywords

Permeability Dust Histamine Macromolecule Myeloma 

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© Springer-Verlag Berlin Heidelberg 1991

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  • R. C. Aalberse

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