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Marchiafava-Bignami Syndrome

  • Jacob Valk
  • Marjo S. van der Knaap

Abstract

Marchiafava-Bignami syndrome (MBS) is a primary degeneration of the corpus callosum occurring in chronic alcoholics. Although a high proportion of reported cases have been Italians, drinking Italian wine, the condition has also been described in many non-Italians drinking non-Italian wine. Most affected cases were middle-aged men whose daily wine consumption had been 2 1 or more for many years. The disease knows three major clinical forms: acute, subacute, and chronic.

Keywords

White Matter Corpus Callosum Anterior Commissure Centrum Semiovale Glial Reaction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • Jacob Valk
    • 1
  • Marjo S. van der Knaap
    • 2
  1. 1.Department of Diagnostic Radiology and NeuroradiologyFree University HospitalAmsterdamThe Netherlands
  2. 2.Department of Child NeurologyAcademic HospitalUtrechtThe Netherlands

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