Soon after the discovery of insulin by Banting and Best in 1921 processes were established for the manufacture of bovine and porcine insulin. Although these first insulins were very impure and caused undesirable side-effects they drastically improved the existence and the prospects of life for hundreds of thousands of diabetics. Later developments in insulin production leading to today’s highly purified products have further improved the efficacy and safety of insulin therapy.
KeywordsHydrolysis Crystallization Urea Citrate Amide
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