Laboratory Diagnosis and Pathogenesis

  • R. Siegert
  • W. Slenczka


After having clarified the etiology [1], we directed our efforts towards a systematic study of establishing a diagnosis [2, 3]. Let us first discuss the isolation of the agent. For this purpose deep-frozen material from the acute phase of the disease was available, namely 17 blood, 6 throat-washings, 4 urine, 5 stool, and 6 liver specimens. The Marburg virus was found in all investigated blood and liver specimens from the febrile phase. These materials contained the highest concentrations of both agent and antigen, thus rendering the demonstration of the virus highly successful, as has also been shown by others [4, 5, 6].


Inclusion Body Liver Specimen Laboratory Diagnosis Marburg Virus Infected Vero Cell 
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© Springer-Verlag Berlin Heidelberg 1971

Authors and Affiliations

  • R. Siegert
  • W. Slenczka

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