Biological Properties of the Marburg Virus

  • W. Slenczka
  • G. Wolff

Abstract

The Marburg virus appears to have a wide host range. Growth of virus was reported in several species of monkeys [2, 3, 4, 14, 15], in guinea pigs [7, 11, 12, 13, 18], and suckling mice [7], in primary and continuous cell lines of various origin [1, 2, 5, 6, 7, 9, 10, 11, 13, 16, 18, 19, 20], and in insects [8]. However, in adult mice [7] and in the fetal organs of chick-embryos [18, 11] no multiplication of virus could be detected. Susceptibility to infection with Marburg virus varies considerably from host to host. In most systems the pathogenicity of the virus for a new host seems to increase gradually during several passages.

Keywords

Cage Germinal Interferon Versene Rabies 

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References

  1. 1.
    Carter G. B., Bright W. F.: Lancet 1968 II, 913–914.CrossRefGoogle Scholar
  2. 2.
    Haas R., Maass G., Müller J., Oehlert W.: Z. med. Mikrobiol. und Immunol. 154, 210–220 (1968).CrossRefGoogle Scholar
  3. 3.
    Haas R., Maass G., Oehlert W.: Med. Klinik 63, 1359–1363 (1968).Google Scholar
  4. 4.
    Haas R., Maass G., Oehlert W.: Primates in Med. 3, 135–137 (1968).Google Scholar
  5. 5.
    Hofmann H., Kunz, Ch.: Zbl. Bakt. I Orig. 208, 344–347 (1968).Google Scholar
  6. 6.
    Kissling R. E., Robinson R. Q., Murphy F. A., Whitfield S. G.: Science 160, 888–890 (1968).PubMedCrossRefGoogle Scholar
  7. 7.
    Kunz, Ch., Hofmann H., Kovac W., Stockinger L.: Wien. klin. Wschr. 80, 161–162 (1968).PubMedGoogle Scholar
  8. 8.
    Kunz, Ch., Hofmann H., Aspöck H.: Zbl. Bakt. I Orig. 208, 347–349 (1968).Google Scholar
  9. 9.
    Maass G. et al.: Morbidity and Mortality: U.S. Department of Health. Follow-up obscure disease related to African Monkeys. Weekly Rep. 17, 223 (1968).Google Scholar
  10. 10.
    Malherbe H., Strickland-Cholmley M.: Lancet 1968 II, 1434.CrossRefGoogle Scholar
  11. 11.
    May G., Knothe H.: Dtsch. med. Wschr. 93, 620–622 (1968).PubMedCrossRefGoogle Scholar
  12. 12.
    Siegert R., Shu H. L., Slenczka W., Peters D., Müller G.: Dtsch. med. Wschr. 92, 2341–2343 (1967).PubMedCrossRefGoogle Scholar
  13. 13.
    Siegert R., Shu H. L., Slenczka W.: Dtsch. med. Wschr. 93, 604–612 (1968).PubMedCrossRefGoogle Scholar
  14. 14.
    Simpson D. I. H., Zlotnik I., Rutter D. A.: Brit. J. Expt. Pathol. XLIX, 458–464 (1968).Google Scholar
  15. 15.
    Simpson D. I. H., Bowen E. T. W., Bright W. F.: Lab. Anim. 2, 75–81 (1968).CrossRefGoogle Scholar
  16. 16.
    Slenczka, W.: 2. Arbeitstagung Dtsch. Ges. Hygiene und Mikrobiologie, Mainz, 7. und 8. Okt. 1968.Google Scholar
  17. 17.
    Slenczka W.: 29th. Symp. of I.A.M.S.: Hazards of Handling Non-Human Primates, 8th to 11th April 1969, Brighton. Lab. Anim. Handb. 4, 143–147 (1969).Google Scholar
  18. 18.
    Smith C. E. G., Simpson D. I. H., Bowen E. T. W., Zlotnik I.: Lancet 1967 II, 1119–1121.CrossRefGoogle Scholar
  19. 19.
    Zlotnik I., Simpson D. I. H., Bright W. F., Bowen E. T. W., Batter-Hatton D.: Brit. J. Expt. Pathol. XLIX, 311–314 (1968).Google Scholar
  20. 20.
    Zlotnik I., Simpson D. I. H.: Lancet (1968) II, 205.CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1971

Authors and Affiliations

  • W. Slenczka
  • G. Wolff

There are no affiliations available

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