Advertisement

Arrhythmogenic mortality in heart-transplant candidates

  • H. -G. Fieguth
  • T. Wahlers
  • H. J. Trappe
  • H. G. Borst

Abstract

Sudden cardiac death represents a major problem in patients awaiting heart transplantation (HTx). A retrospective analysis of 1019 patients accepted for HTx revealed a high actuarial risk for sudden death accounting to 14% after 1 year and 20% after 2 years waiting time. Unterlying disease and hemodynamic characteristics had no predictive value. The use of implantable cardioverter/defibrillator therapy is discussed.

Key words

Heart transplantation Sudden cardiac death Myocardial death Implantable cardioverter/ defibrillator therapy 

References

  1. 1.
    Goldman S, Johnson G, Cohn J, et al, VHeFT Cooperative Study Group (1993) Circulation 87 (VI): 24–31Google Scholar
  2. 2.
    Defibrilat Study Group (1991) J Am Coll Cardiol 68: 545–546Google Scholar
  3. 3.
    Stevenson WD, Stevenson LD, Middlekauf HR, Saxon LA (1993) Circulation 88: 6 2953–2961PubMedCrossRefGoogle Scholar
  4. 4.
    Packer M (1992) Circulation 85: 1 (I): 50–56Google Scholar
  5. 5.
    Loisance DY, Deleuze PH, Houei R, et al (1993) Ann Thorac Surg 55: 310–313PubMedCrossRefGoogle Scholar
  6. 6.
    Jeevanandam V, Bielefeld M, Auteri J, et al (1992) Circulation 86 (II): 276–279Google Scholar
  7. 7.
    The Cardiac Arrhythmia Suppression Trial (CAST) Investigators (1991) N Engl J Med 324: 781–788Google Scholar
  8. 8.
    Metha D, Saksena S, Krol RB, et al (1993) PACE 16 (II): 179–185CrossRefGoogle Scholar
  9. 9.
    Fieguth HG, Wahlers T, Trappe HJ, et al (1993) Cor Europ I: 2 75–77Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1996

Authors and Affiliations

  • H. -G. Fieguth
    • 1
  • T. Wahlers
    • 1
  • H. J. Trappe
    • 2
  • H. G. Borst
    • 1
  1. 1.Division of Cardiovascular SurgeryHannover Medical SchoolHannoverGermany
  2. 2.Division of CardiologyHannover Medical SchoolHannoverGermany

Personalised recommendations