Preimplantation Diagnosis

  • I. Liebaers
  • W. Lissens
  • K. Sermon
  • E. Van Assche
  • C. Staessen
  • H. Joris
  • A. Van Steirteghem


The ability to hyperstimulate the ovaries, retrieve ova, and fertilize them has made in vitro fertilization (IVF) a safe and effective treatment for infertility. Several tens of thousands of children have been born to couples who were unable to conceive otherwise. IVF has opened the door to several reproductive advances such as oocyte donation, embryo freezing, and assisted fertilization procedures such as the recently introduced procedure of intracytoplasmic sperm injection (ICSI) to alleviate severe male-factor infertility. IVF also made preimplantation genetic diagnosis possible as an option to couples at risk for serious genetic disease. Rather than terminating a pregnancy after conventional prenatal diagnosis, embryo analysis permits selection of embryos without disease to be replaced in the uterus.


Preimplantation Genetic Diagnosis Polar Body Myotonic Dystrophy Preimplantation Embryo Cleavage Stage Embryo 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1997

Authors and Affiliations

  • I. Liebaers
  • W. Lissens
  • K. Sermon
  • E. Van Assche
  • C. Staessen
  • H. Joris
  • A. Van Steirteghem

There are no affiliations available

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