Zusammenfassung
Kardiovaskuläre Manifestationen der Hyperthyreose, wie Tachykardie, Tachyarrhythmie, Vorhofflimmern und systolischer Hochdruck, stehen häufig subjektiv und objektiv im Zentrum der klinischen Symptomatologie [37, 40, 46]. Sie sind bei Schilddrüsenfunktionsstörungen nicht nur eine wesentliche Hilfe in der Diagnostik, sondern auch in der Beurteilung des therapeutischen Erfolges. Die im Rahmen der Hyperthyreose beobachteten hämodynamischen Veränderungen, wie gesteigertes Herzminutenvolumen, erhöhtes Blutvolumen sowie reduzierter peripherer Gefäßwiderstand führen in ausgeprägten Fällen zur Steigerung des systolischen und Senkung des diastolischen Blutdruckes und damit zum typischen Pulsus celer et altus des hyperkinetischen Kreislaufsyndroms.
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Literatur
Amidi M, Leon DF, Groot WJ de, Krötz FW, Leonard JJ (1968) Effect of the thyroid state on myocardial contractility and ventricular ejection rate in man. Circulation 38: 229
Aoki VS, Wilson WR, Theilen EO, Lukensmeyer WW, Leaverton PE (1967) The effects of triiodothyronine on hemodynamic responses to epinephrine and norepinephrine in man. J Pharmacol Exp Ther 157: 62
Brewster WR, Isaacs JP, Osgood PF, King TL (1956) The hemodynamic and metabolic interrelationships in the activity of epinephrine, nor-epinephrine and the thyroid hormones. Circulation 13: 1
Buccino RA, Spann JF, Pool PE, Sonnenblick EH, Braunwald E (1967) Influence of the thyroid state on the intrinsic contractile properties and energy stores of the myocardium. J Clin Invest 46: 1669
Christensen NJ (1972) Increased levels of plasma noradrenaline in hypothyroidism. J Clin Endocrinol Metab 35: 359
Coulombe P, Dussault JH, Letarte J, Simard SJ (1976) Catecholamine metabolism in thyroid diseases. I. Epinephrine secretion rate in hyperthyroidism and hypothyroidism. J Clin Endocrinol Metab 42: 125
Coulombe P, Dussault JH, Walker P (1976) Plasma catecholamine concentrations in hyperthyroidism and hypothyroidism. Metabolism 25: 973
Coulombe P, Dussault JH, Walker P (1977) Catecholamine metabolism in thyroid disease. II. Norepinephrine secretion rate in hyperthyroidism and hypothyroidism. J Clin Endocrinol Me-tab 44: 1185
Crawford DG, Fairchild HM, Guyton AC (1959) Oxygen lack as a possible cause of reactive hyperemia. J Am Physiol 197: 613
Distler A, Philipp T, Lüth B, Zschiedrich H, Cordes U (1981) Interrelationships between plasma norepinephrine and blood pressure response to norepinephrine in normotension and hypertension. In: Laragh JH, Bühler FR, Seldin DW (eds). Frontiers in Hypertension Research. Springer, New York, S 297–300
Doherty JE, Perkins WH (1966) Digoxin metabolism in hypo-and hyperthyroidism. Studies with tritiated digoxin in thyroid disease. Ann Intern Med 64: 489
Gibson JG, Harris AW (1939) Clinical studies of the blood volume. V. Hyperthyroidism and myxedema. J Clin Invest 18: 59
Goodkind MJ (1966) The influence of thyroid hormone on myocardial metabolism of norepinephrine in the guinea pig. J Pharmacol Exp Ther 154: 531
Goodkind MJ, Dambach GE, Thyrum PT, Luchi RJ (1974) Effect of thyroxine on ventricular myocardial contractility and ATPase activity in guinea pigs. Am J Physiol 226: 66
Groot WJ de, Leonard JJ (1970) Hyperthyroidism as a high cardiac output state. Am Heart J 79: 265
Grossman W, Robin NI, Johnson LW, Brooks HL, Selenkow HA, Dexter L (1971) The enhanced myocardial contractility of thyrotoxicosis. Ann Intern Med 74: 869
Guttler RB, Croxson MS, Quattro VL de, Warren DW, Otis CL, Nicoloff JT (1977) Effects of thyroid hormone on plasma adenosine 3’, 5’-monophosphate production in man. Metabolism 26: 1155
Guyton AC (1963) Effect of tissue oxygen need on cardiac output. In: Guyton AC, Jones CE, Coleman TG (eds) Circulatory physiology: cardiac output and its regulation. Saunders Company, Eastbourne, p 301
Harrison TS (1964) Adrenal medullary and thyroid relationships. Physiol Rev 44: 161
Hertzman AB (1959) Vasomotor regulation of cutaneous circulation. Physiol Rev 39: 280
Hirvonen L, Lang H (1962) Thyroid activity and heart rate. Proc Soc Exp Biol Med 109: 284
Huckabee WE (1961) Effects of phosphorylative uncoupling in tissues on cardiac output of intact animals. Fed Proc 20: 13 (Abstract)
Humerfelt S, Müller O, Storstein O (1958) The circulation in hyperthyroidism: a cardiac catheterization study before and after treatment. Am Heart J 56: 87
Hurxthal LM (1931) Blood pressure before and after operation in hyperthyroidism. Arch Intern Med 47: 167
Jose AD (1966) Effect of combined sympathetic and parasympathetic blockade on heart rate and cardiac function in man. Am J Cardiol 18: 476
Kontos HA, Shapiro W, Mauck HP, Richardson DW, Patterson JL, Sharpe AR (1965) Mechanism of certain abnormalities of the circulation to the limbs in thyrotoxicosis. J Clin Invest 44: 947
Krötz F, Groot WJ de, Leonard JJ, Warren JV (1962) The relationship of oxygen consumption to hemodynamic response in hypermetabolic states. Circ Res 10: 19 (Abstract)
Levey GS (1971) Catecholamine sensitivity, thyroid hormone and the heart. Am J Med 50: 413
Levey GS, Epstein SE (1969) Myocardial adenyl cyclase: activation by thyroid hormones and evidence for two adenyl cyclase systems. J Clin Invest 48: 1663
Levey GS, Skelton CL, Epstein SE (1969) Influence of hyperthyroidism on the effects of norepinephrine on myocardial adenyl cyclase activity and contractile state. Endocrinology 85: 1004
Margolius HS, Gaffney TE (1965) The effects of injected norepinephrine and sympathetic nerve stimulation in hypothyroid and hyperthyroid dogs. J Pharmacol Exp Ther 149: 329
Massey DG, Becklake MR, McKenzie JM, Bates DV (1967) Circulatory and ventilatory response to exercise in thyrotoxicosis. N Engl J Med 276: 1104
Pool PE, Skelton CL, Seagren SC, Braunwald E (1968) Chemical energetics of cardiac muscle in hyperthyroidism. J Clin Invest 47: 80 (Abstract)
Ross JM, Fairchild HM, Weldy J, Guyton AC (1962) Autoregulation of blood flow by oxygen lack. Am J Physiol 202: 21
Schoot JB van der, Moran NC (1965) An experimental evaluation of the reputed influence of thyroxine on the cardiovascular effects of catecholamines. J Pharmacol Exp Ther 149: 336
Skelton CL, Coleman NH, Wildenthal K, Braunwald E (1970) Augmentation of myocardial oxygen consumption in hyperthyroid cats. Circ Res 37: 301
Sobel BE, Braunwald E (1971) Cardiovascular system. In: Werner SC, Ingbar SH (eds) The Thyroid. Harper & Row, Hagerstown, Maryland, p 551
Stainsby WN (1962) Autoregulation of blood flow in skeletal muscle during increased metabolic activity. Am J Physiol 202: 273
Stoffer SS, Jiang NS, Gorman CA, Pikler GM (1973) Plasma catecholamines in hypothyroidism and hyperthyroidism. J Clin Endocrinol Metab 36: 587
Summers VK, Surtees SJ (1961) Thyrotoxicosis and heart disease. Acta Med Scand 169: 661
Taylor RR (1970) Contractile properties of cardiac muscle in hyperthyroidism. Circ Res 27: 539
Tech PC, Cheah JS, Chia BL (1974) Effect of adrenergic blockade and specific antithyroid therapy on electrocardiographic changes in hyperthyroidism. Am J Med Sci 268: 157
Theilen EO, Wilson WR (1967) Hemodynamic effects of peripheral vasoconstriction in normal and thyrotoxic subjects. J Appl Physiol 22: 207
Thompson WO, Dickie LFN, Morris AE, Hilkevitch BH (1931) The high incidence of hypertension in toxic goiter and in myxedema. Endocrinology 15: 265
Vana S, Nemec J (1976) Critical evaluation of the diagnostic value of systolic time intervals in the diagnosis of functional thyroid diseases. Comparison of results in a highly selected and a non-selected group of patients in relation to the blood PBI and T4I levels. Endokrinologie 68: 164
Wenger NK, Herndon EG (1974) Endocrine and metabolic disorders. In: Hurst JW (ed) The heart, arteries and veins. McGraw-Hill Kogakusha, p 1478
Wilson WR, Theilen EO, Fletcher FW (1964) Pharmacodynamic effects of betaadrenergic receptor blockade in patients with hyperthyroidism. J Clin Invest 43: 1697
Wilson WR, Theilen EO, Hege JH, Valenca MR (1966) Effects of beta-adrenergic receptor blockade in normal subjects before, during, and after triiodothyronine-induced hypermetabolism. J Clin Invest 45: 1159
Wiswell JG, Hurwitz GE, Coronho V, Bing OHL, Child DL (1963) Urinary catecholamines and their metabolites in hyperthyroidism and hypothyroidism. J Clin Endocrinol Metab 23: 1102
Wurtman RJ, Kopin IJ, Axelrod J (1963) Thyroid function and the cardiac disposition of catecholamines. Endocrinology 73: 63
Young RT, Herle AJ van, Rodbard D (1976) Improved diagnosis and management of hyper-and hypothyroidism by timing the arterial sounds. J Clin Endocrinol Metab 42: 330
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Waldhäusl, W.K., Bratusch-Marrain, P.R. (1984). Hypertonie bei Hyperthyreose. In: Rosenthal, J. (eds) Arterielle Hypertonie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-00760-0_13
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